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Carbon ion irradiation enhances the antitumor efficacy of dual immune checkpoint blockade therapy both for local and distant sites in murine osteosarcoma

Carbon ion radiotherapy has been utilized even for X-ray resistant tumors. However, control of distant metastasis remains a major challenge in carbon ion irradiation. We investigated whether carbon ion irradiation combined with dual immune checkpoint blockade therapy (anti-PD-L1 and anti-CTLA-4 anti...

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Detalles Bibliográficos
Autores principales:	Takahashi, Yutaka, Yasui, Tomohiro, Minami, Kazumasa, Tamari, Keisuke, Hayashi, Kazuhiko, Otani, Keisuke, Seo, Yuji, Isohashi, Fumiaki, Koizumi, Masahiko, Ogawa, Kazuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363009/ https://www.ncbi.nlm.nih.gov/pubmed/30774761 http://dx.doi.org/10.18632/oncotarget.26551

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