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Structural basis of human ORP1-Rab7 interaction for the late-endosome and lysosome targeting

Oxysterol-binding protein (OSBP) and OSBP-related proteins (ORPs) constitute a family of lipid transfer proteins conserved in eukaryotes. ORP1 transports cholesterol at the interface between the late endosomes/lysosomes (LELs) and the endoplasmic reticulum (ER). ORP1 is targeted to the endosomal mem...

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Detalles Bibliográficos
Autores principales:	Tong, Junsen, Tan, Lingchen, Chun, ChangJu, Im, Young Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363164/ https://www.ncbi.nlm.nih.gov/pubmed/30721249 http://dx.doi.org/10.1371/journal.pone.0211724

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