Dissecting the roles of β-arrestin2 and GSK-3 signaling in 5-HT1BR-mediated perseverative behavior and prepulse inhibition deficits in mice

Serotonin-1B receptors (5-HT1BRs) modulate perseverative behaviors and prepulse inhibition (PPI) in humans and mice. These inhibitory G-protein-coupled receptors signal through a canonical G-protein-coupled pathway that is modulated by GSK-3β, and a noncanonical pathway mediated by the adaptor prote...

Descripción completa

Detalles Bibliográficos
Autores principales: Thompson, Summer L., Dulawa, Stephanie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363181/
https://www.ncbi.nlm.nih.gov/pubmed/30721232
http://dx.doi.org/10.1371/journal.pone.0211239

Ejemplares similares

Ejemplares similares