Interplay of lamin A and lamin B LADs on the radial positioning of chromatin

Immunosuppressive drugs such as cyclosporin A (CsA) can elicit hepatotoxicity by affecting gene expression. Here, we address the link between CsA and large-scale chromatin organization in HepG2 hepatocarcinoma cells. We show the existence of lamina-associated domains (LADs) interacting with lamin A,...

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Detalles Bibliográficos
Autores principales: Forsberg, Frida, Brunet, Annaël, Ali, Tharvesh M. Liyakat, Collas, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363278/
https://www.ncbi.nlm.nih.gov/pubmed/30663495
http://dx.doi.org/10.1080/19491034.2019.1570810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363278/
https://www.ncbi.nlm.nih.gov/pubmed/30663495
http://dx.doi.org/10.1080/19491034.2019.1570810

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