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Organization of ATP-gated P2X1 receptor intracellular termini in apo and desensitized states

The human P2X1 receptor (hP2X1R) is a trimeric ligand-gated ion channel opened by extracellular ATP. The intracellular amino and carboxyl termini play significant roles in determining the time-course and regulation of channel gating—for example, the C terminus regulates recovery from the desensitize...

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Detalles Bibliográficos
Autores principales:	Fryatt, Alistair G., Dayl, Sudad, Stavrou, Anastasios, Schmid, Ralf, Evans, Richard J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363416/ https://www.ncbi.nlm.nih.gov/pubmed/30626615 http://dx.doi.org/10.1085/jgp.201812108

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