Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis

Heart failure due to dilated cardiomyopathy is frequently caused by myocarditis. However, the pathogenesis of myocarditis remains incompletely understood. Here, we report the presence of neutrophil extracellular traps (NETs) in cardiac tissue of patients and mice with myocarditis. Inhibition of NET...

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Detalles Bibliográficos
Autores principales: Weckbach, Ludwig T., Grabmaier, Ulrich, Uhl, Andreas, Gess, Sebastian, Boehm, Felicitas, Zehrer, Annette, Pick, Robert, Salvermoser, Melanie, Czermak, Thomas, Pircher, Joachim, Sorrelle, Noah, Migliorini, Mary, Strickland, Dudley K., Klingel, Karin, Brinkmann, Volker, Abu Abed, Ulrike, Eriksson, Urs, Massberg, Steffen, Brunner, Stefan, Walzog, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363424/
https://www.ncbi.nlm.nih.gov/pubmed/30647120
http://dx.doi.org/10.1084/jem.20181102

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