Cargando…

Wnt5a induces and maintains prostate cancer cells dormancy in bone

In a substantial fraction of prostate cancer (PCa) patients, bone metastasis appears after years or even decades of latency. Canonical Wnt/β-catenin signaling has been proposed to be implicated in dormancy of cancer cells. However, how these tumor cells are kept dormant and recur under control of Wn...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ren, Dong, Dai, Yuhu, Yang, Qing, Zhang, Xin, Guo, Wei, Ye, Liping, Huang, Shuai, Chen, Xu, Lai, Yingrong, Du, Hong, Lin, Chuyong, Peng, Xinsheng, Song, Libing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363426/ https://www.ncbi.nlm.nih.gov/pubmed/30593464 http://dx.doi.org/10.1084/jem.20180661

Ejemplares similares

The TGF-β signalling negative regulator PICK1 represses prostate cancer metastasis to bone
por: Dai, Yuhu, et al.
Publicado: (2017)

Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-κB signaling pathway
por: Ren, Dong, et al.
Publicado: (2017)

Copy number gain of ZEB1 mediates a double-negative feedback loop with miR-33a-5p that regulates EMT and bone metastasis of prostate cancer dependent on TGF-β signaling
por: Dai, Yuhu, et al.
Publicado: (2019)

SMAD3/SP1 complex‐mediated constitutive active loop between lncRNA PCAT7 and TGF‐β signaling promotes prostate cancer bone metastasis
por: Lang, Chuandong, et al.
Publicado: (2020)

MAZ promotes prostate cancer bone metastasis through transcriptionally activating the KRas-dependent RalGEFs pathway
por: Yang, Qing, et al.
Publicado: (2019)

miR-1266 Contributes to Pancreatic Cancer Progression and Chemoresistance by the STAT3 and NF-κB Signaling Pathways
por: Zhang, Xin, et al.
Publicado: (2018)

The long transcript of lncRNA TMPO-AS1 promotes bone metastases of prostate cancer by regulating the CSNK2A1/DDX3X complex in Wnt/β-catenin signaling
por: Wang, Min, et al.
Publicado: (2023)

BHLHE22 drives the immunosuppressive bone tumor microenvironment and associated bone metastasis in prostate cancer
por: Yin, Chi, et al.
Publicado: (2023)

m(6)A modification of lncRNA PCAT6 promotes bone metastasis in prostate cancer through IGF2BP2‐mediated IGF1R mRNA stabilization
por: Lang, Chuandong, et al.
Publicado: (2021)

Identification of miRs-143 and -145 that Is Associated with Bone Metastasis of Prostate Cancer and Involved in the Regulation of EMT
por: Peng, Xinsheng, et al.
Publicado: (2011)

Prostate Cancer Dormancy and Reactivation in Bone Marrow
por: Singh, Deepak K., et al.
Publicado: (2021)

PHF21B overexpression promotes cancer stem cell-like traits in prostate cancer cells by activating the Wnt/β-catenin signaling pathway
por: Li, Qiji, et al.
Publicado: (2017)

Deletion of Wild-type p53 Facilitates Bone Metastatic Function by Blocking the AIP4 Mediated Ligand-Induced Degradation of CXCR4
por: Li, Qiji, et al.
Publicado: (2022)

TGF-β maintains dormancy of prostatic stem cells in the proximal region of ducts
por: Salm, Sarah N., et al.
Publicado: (2005)

Transcriptional downregulation of miR-133b by REST promotes prostate cancer metastasis to bone via activating TGF-β signaling
por: Huang, Shuai, et al.
Publicado: (2018)

Nuclear orphan receptor NR2F6 confers cisplatin resistance in epithelial ovarian cancer cells by activating the Notch3 signaling pathway
por: Li, Han, et al.
Publicado: (2019)

MYBL2 disrupts the Hippo-YAP pathway and confers castration resistance and metastatic potential in prostate cancer
por: Li, Qiji, et al.
Publicado: (2021)

Novel Dormancy Mechanism of Castration Resistance in Bone Metastatic Prostate Cancer Organoids
por: Lee, Sanghee, et al.
Publicado: (2022)

Bone morphogenetic protein 7 in dormancy and metastasis of prostate cancer stem-like cells in bone
por: Kobayashi, Aya, et al.
Publicado: (2012)

Bone morphogenetic protein 7 in dormancy and metastasis of prostate cancer stem-like cells in bone
por: Kobayashi, Aya, et al.
Publicado: (2011)

The roles of metabolic pathways in maintaining primary dormancy of Pinus koraiensis seeds
por: Song, Yuan, et al.
Publicado: (2019)

Prostate cancer cell‐intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone
por: Owen, Katie L, et al.
Publicado: (2020)

Abscisic acid regulates dormancy of prostate cancer disseminated tumor cells in the bone marrow
por: Jung, Younghun, et al.
Publicado: (2020)

Ras and Wnt Interaction Contribute in Prostate Cancer Bone Metastasis
por: Lin, Shian-Ren, et al.
Publicado: (2020)

BCL6 regulates brown adipocyte dormancy to maintain thermogenic reserve and fitness
por: Kutyavin, Vassily I., et al.
Publicado: (2019)

Axl is required for TGF-β2-induced dormancy of prostate cancer cells in the bone marrow
por: Yumoto, Kenji, et al.
Publicado: (2016)

Itraconazole perturbs colorectal cancer dormancy through SUFU-mediated WNT inhibition
por: Popova, Semiramis A., et al.
Publicado: (2018)

PSMA-Targeting Reduction-Cleavable Hyperbranched Polyamide-Amine Gene Delivery System to Treat the Bone Metastases of Prostate Cancer
por: Ye, Yongheng, et al.
Publicado: (2020)

Thymosin beta 10 is a key regulator of tumorigenesis and metastasis and a novel serum marker in breast cancer
por: Zhang, Xin, et al.
Publicado: (2017)

Osteoblasts and osteoclasts: an important switch of tumour cell dormancy during bone metastasis
por: Dai, Rongchen, et al.
Publicado: (2022)

Fibroblasts in cancer dormancy: foe or friend?
por: Dai, Li, et al.
Publicado: (2021)

Upregulation of E2F8 promotes cell proliferation and tumorigenicity in breast cancer by modulating G1/S phase transition
por: Ye, Liping, et al.
Publicado: (2016)

GINS2 is a novel prognostic biomarker and promotes tumor progression in early-stage cervical cancer
por: Ouyang, Fei, et al.
Publicado: (2017)

GINS2 is a novel prognostic biomarker and promotes tumor progression in early-stage cervical cancer
por: Ouyang, Fei, et al.
Publicado: (2021)

Downregulation of miR-141-3p promotes bone metastasis via activating NF-κB signaling in prostate cancer
por: Huang, Shuai, et al.
Publicado: (2017)

Cancer Dormancy: A Regulatory Role for Endogenous Immunity in Establishing and Maintaining the Tumor Dormant State
por: Baxevanis, Constantin N., et al.
Publicado: (2015)

Downregulation of miR-19a-3p promotes invasion, migration and bone metastasis via activating TGF-β signaling in prostate cancer
por: Wa, Qingde, et al.
Publicado: (2018)

Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling
por: Tang, Yubo, et al.
Publicado: (2018)

Single-cell sequencing reveals MYC targeting gene MAD2L1 is associated with prostate cancer bone metastasis tumor dormancy
por: Wang, Xing, et al.
Publicado: (2022)

Cellular Adhesion Promotes Prostate Cancer Cells Escape from Dormancy
por: Ruppender, Nazanin, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_6059hmt0o95i4j1atu4omdfin3