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LUBAC determines chemotherapy resistance in squamous cell lung cancer

Lung squamous cell carcinoma (LSCC) and adenocarcinoma (LADC) are the most common lung cancer subtypes. Molecular targeted treatments have improved LADC patient survival but are largely ineffective in LSCC. The tumor suppressor FBW7 is commonly mutated or down-regulated in human LSCC, and oncogenic...

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Detalles Bibliográficos
Autores principales:	Ruiz, E. Josue, Diefenbacher, Markus E., Nelson, Jessica K., Sancho, Rocio, Pucci, Fabio, Chakraborty, Atanu, Moreno, Paula, Annibaldi, Alessandro, Liccardi, Gianmaria, Encheva, Vesela, Mitter, Richard, Rosenfeldt, Mathias, Snijders, Ambrosius P., Meier, Pascal, Calzado, Marco A., Behrens, Axel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363428/ https://www.ncbi.nlm.nih.gov/pubmed/30642944 http://dx.doi.org/10.1084/jem.20180742

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