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Detyrosinated microtubules spatially constrain lysosomes facilitating lysosome–autophagosome fusion
Microtubule post-translational modifications impart functional diversity to microtubules by affecting their dynamics, organization, and interaction with proteins. Using super-resolution microscopy, we show that only a small subpopulation of microtubules are detyrosinated in epithelial cells, while a...
Autores principales: | Mohan, Nitin, Sorokina, Elena M., Verdeny, Ione Vilanova, Alvarez, Angel Sandoval, Lakadamyali, Melike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363446/ https://www.ncbi.nlm.nih.gov/pubmed/30567713 http://dx.doi.org/10.1083/jcb.201807124 |
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