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BAR scaffolds drive membrane fission by crowding disordered domains

Cellular membranes are continuously remodeled. The crescent-shaped bin-amphiphysin-rvs (BAR) domains remodel membranes in multiple cellular pathways. Based on studies of isolated BAR domains in vitro, the current paradigm is that BAR domain–containing proteins polymerize into cylindrical scaffolds t...

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Detalles Bibliográficos
Autores principales: Snead, Wilton T., Zeno, Wade F., Kago, Grace, Perkins, Ryan W., Richter, J Blair, Zhao, Chi, Lafer, Eileen M., Stachowiak, Jeanne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363457/
https://www.ncbi.nlm.nih.gov/pubmed/30504247
http://dx.doi.org/10.1083/jcb.201807119

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