ENSA and ARPP19 differentially control cell cycle progression and development

Greatwall (GWL) is an essential kinase that indirectly controls PP2A-B55, the phosphatase counterbalancing cyclin B/CDK1 activity during mitosis. In Xenopus laevis egg extracts, GWL-mediated phosphorylation of overexpressed ARPP19 and ENSA turns them into potent PP2A-B55 inhibitors. It has been show...

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Detalles Bibliográficos
Autores principales: Hached, Khaled, Goguet, Perrine, Charrasse, Sophie, Vigneron, Suzanne, Sacristan, Maria P., Lorca, Thierry, Castro, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363464/
https://www.ncbi.nlm.nih.gov/pubmed/30626720
http://dx.doi.org/10.1083/jcb.201708105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363464/
https://www.ncbi.nlm.nih.gov/pubmed/30626720
http://dx.doi.org/10.1083/jcb.201708105

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