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ENSA and ARPP19 differentially control cell cycle progression and development
Greatwall (GWL) is an essential kinase that indirectly controls PP2A-B55, the phosphatase counterbalancing cyclin B/CDK1 activity during mitosis. In Xenopus laevis egg extracts, GWL-mediated phosphorylation of overexpressed ARPP19 and ENSA turns them into potent PP2A-B55 inhibitors. It has been show...
Autores principales: | Hached, Khaled, Goguet, Perrine, Charrasse, Sophie, Vigneron, Suzanne, Sacristan, Maria P., Lorca, Thierry, Castro, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363464/ https://www.ncbi.nlm.nih.gov/pubmed/30626720 http://dx.doi.org/10.1083/jcb.201708105 |
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