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Albumin-linked prostate-specific antigen-activated thapsigargin- and niclosamide-based molecular grenades targeting the microenvironment in metastatic castration-resistant prostate cancer
Localized prostate cancer is curable via annihilation of the entire cancer neighborhood by surgery or local radiation. Unfortunately, once metastatic, no available therapy is curative. The vast majority will die despite aggressive systemic combinational androgen-ablation therapies. Thus, there is an...
Autores principales: | Akinboye, Emmanuel S., Brennen, W. Nathaniel, Denmeade, Samuel R., Isaacs, John T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Second Military Medical University
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363604/ https://www.ncbi.nlm.nih.gov/pubmed/30775253 http://dx.doi.org/10.1016/j.ajur.2018.11.004 |
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