A Human iPSC-derived 3D platform using primary brain cancer cells to study drug development and personalized medicine

A high throughput histology (microTMA) platform was applied for testing drugs against tumors in a novel 3D heterotypic glioblastoma brain sphere (gBS) model consisting of glioblastoma tumor cells, iPSC-derived neurons, glial cells and astrocytes grown in a spheroid. The differential responses of gBS...

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Detalles Bibliográficos
Autores principales: Plummer, Simon, Wallace, Stephanie, Ball, Graeme, Lloyd, Roslyn, Schiapparelli, Paula, Quiñones-Hinojosa, Alfredo, Hartung, Thomas, Pamies, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363784/
https://www.ncbi.nlm.nih.gov/pubmed/30723234
http://dx.doi.org/10.1038/s41598-018-38130-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363784/
https://www.ncbi.nlm.nih.gov/pubmed/30723234
http://dx.doi.org/10.1038/s41598-018-38130-0

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