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Mapping the pH Sensors Critical for Host Cell Entry by a Complex Nonenveloped Virus

Bluetongue virus (BTV), in the family Reoviridae, is an insect-borne, double-capsid virus causing hemorrhagic disease in livestock around the world. Here, we elucidate how outer capsid proteins VP2 and VP5 coordinate cell entry of BTV. To identify key functional residues, we used atomic-level struct...

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Detalles Bibliográficos
Autores principales:	Wu, Weining, Celma, Cristina C., Kerviel, Adeline, Roy, Polly
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Virus-Cell Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363992/ https://www.ncbi.nlm.nih.gov/pubmed/30518645 http://dx.doi.org/10.1128/JVI.01897-18

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