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PDE4 and Epac1 Synergistically Promote Rectal Carcinoma via the cAMP Pathway

OBJECTIVE: To assess the expression levels of exchange protein 1 directly activated by cAMP (Epac1) and phosphodiesterase 4 (PDE4) in rectal carcinoma, and their associations with clinicopathological indexes. In addition, the associations of PDE4 and Epac1 with A-kinase anchor protein 95, connexin 4...

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Detalles Bibliográficos
Autores principales: Kong, Xiangyu, Ai, Ganghao, Wang, Dai, Chen, Renzhen, Guo, Dongbei, Yao, Youliang, Wang, Kai, Liang, Guiye, Qi, Fengjie, Liu, Wenzhi, Zhang, Yongxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364102/
https://www.ncbi.nlm.nih.gov/pubmed/30809467
http://dx.doi.org/10.1155/2019/7145198