The impact of balanced reciprocal translocation - 46,XX,t(7;17) (p13;q24) probably involving the SOX9 gene in the in vitro fertilization with own oocytes evaluated by preimplantation genetic testing or donated oocytes

Preimplantation genetic testing (PGT) for in vitro fertilization (IVF) - also known as PGT for Structural Rearrangements (PGT-SR) - has emerged as an option for at-risk couples carrying balanced translocations. The female in the couple featured in this case report is a carrier of a balanced reciproc...

Descripción completa

Detalles Bibliográficos
Autores principales: Peregrino, Pedro F.M., Gomes, Alecsandra, Fujii, Mariana, Bonetti, Tatiana C.S., Riboldi, Marcia, Monteleone, Pedro A.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brazilian Society of Assisted Reproduction 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364276/
https://www.ncbi.nlm.nih.gov/pubmed/30264949
http://dx.doi.org/10.5935/1518-0557.20180066
_version_ 1783393236225622016
author Peregrino, Pedro F.M.
Gomes, Alecsandra
Fujii, Mariana
Bonetti, Tatiana C.S.
Riboldi, Marcia
Monteleone, Pedro A.A.
author_facet Peregrino, Pedro F.M.
Gomes, Alecsandra
Fujii, Mariana
Bonetti, Tatiana C.S.
Riboldi, Marcia
Monteleone, Pedro A.A.
author_sort Peregrino, Pedro F.M.
collection PubMed
description Preimplantation genetic testing (PGT) for in vitro fertilization (IVF) - also known as PGT for Structural Rearrangements (PGT-SR) - has emerged as an option for at-risk couples carrying balanced translocations. The female in the couple featured in this case report is a carrier of a balanced reciprocal translocation who underwent IVF. PGT showed all her embryos were aneuploid. She subsequently had two cycles using donor oocytes, which ended in miscarriages.
format Online
Article
Text
id pubmed-6364276
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Brazilian Society of Assisted Reproduction
record_format MEDLINE/PubMed
spelling pubmed-63642762019-02-06 The impact of balanced reciprocal translocation - 46,XX,t(7;17) (p13;q24) probably involving the SOX9 gene in the in vitro fertilization with own oocytes evaluated by preimplantation genetic testing or donated oocytes Peregrino, Pedro F.M. Gomes, Alecsandra Fujii, Mariana Bonetti, Tatiana C.S. Riboldi, Marcia Monteleone, Pedro A.A. JBRA Assist Reprod Case Report Preimplantation genetic testing (PGT) for in vitro fertilization (IVF) - also known as PGT for Structural Rearrangements (PGT-SR) - has emerged as an option for at-risk couples carrying balanced translocations. The female in the couple featured in this case report is a carrier of a balanced reciprocal translocation who underwent IVF. PGT showed all her embryos were aneuploid. She subsequently had two cycles using donor oocytes, which ended in miscarriages. Brazilian Society of Assisted Reproduction 2019 /pmc/articles/PMC6364276/ /pubmed/30264949 http://dx.doi.org/10.5935/1518-0557.20180066 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Peregrino, Pedro F.M.
Gomes, Alecsandra
Fujii, Mariana
Bonetti, Tatiana C.S.
Riboldi, Marcia
Monteleone, Pedro A.A.
The impact of balanced reciprocal translocation - 46,XX,t(7;17) (p13;q24) probably involving the SOX9 gene in the in vitro fertilization with own oocytes evaluated by preimplantation genetic testing or donated oocytes
title The impact of balanced reciprocal translocation - 46,XX,t(7;17) (p13;q24) probably involving the SOX9 gene in the in vitro fertilization with own oocytes evaluated by preimplantation genetic testing or donated oocytes
title_full The impact of balanced reciprocal translocation - 46,XX,t(7;17) (p13;q24) probably involving the SOX9 gene in the in vitro fertilization with own oocytes evaluated by preimplantation genetic testing or donated oocytes
title_fullStr The impact of balanced reciprocal translocation - 46,XX,t(7;17) (p13;q24) probably involving the SOX9 gene in the in vitro fertilization with own oocytes evaluated by preimplantation genetic testing or donated oocytes
title_full_unstemmed The impact of balanced reciprocal translocation - 46,XX,t(7;17) (p13;q24) probably involving the SOX9 gene in the in vitro fertilization with own oocytes evaluated by preimplantation genetic testing or donated oocytes
title_short The impact of balanced reciprocal translocation - 46,XX,t(7;17) (p13;q24) probably involving the SOX9 gene in the in vitro fertilization with own oocytes evaluated by preimplantation genetic testing or donated oocytes
title_sort impact of balanced reciprocal translocation - 46,xx,t(7;17) (p13;q24) probably involving the sox9 gene in the in vitro fertilization with own oocytes evaluated by preimplantation genetic testing or donated oocytes
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364276/
https://www.ncbi.nlm.nih.gov/pubmed/30264949
http://dx.doi.org/10.5935/1518-0557.20180066
work_keys_str_mv AT peregrinopedrofm theimpactofbalancedreciprocaltranslocation46xxt717p13q24probablyinvolvingthesox9geneintheinvitrofertilizationwithownoocytesevaluatedbypreimplantationgenetictestingordonatedoocytes
AT gomesalecsandra theimpactofbalancedreciprocaltranslocation46xxt717p13q24probablyinvolvingthesox9geneintheinvitrofertilizationwithownoocytesevaluatedbypreimplantationgenetictestingordonatedoocytes
AT fujiimariana theimpactofbalancedreciprocaltranslocation46xxt717p13q24probablyinvolvingthesox9geneintheinvitrofertilizationwithownoocytesevaluatedbypreimplantationgenetictestingordonatedoocytes
AT bonettitatianacs theimpactofbalancedreciprocaltranslocation46xxt717p13q24probablyinvolvingthesox9geneintheinvitrofertilizationwithownoocytesevaluatedbypreimplantationgenetictestingordonatedoocytes
AT riboldimarcia theimpactofbalancedreciprocaltranslocation46xxt717p13q24probablyinvolvingthesox9geneintheinvitrofertilizationwithownoocytesevaluatedbypreimplantationgenetictestingordonatedoocytes
AT monteleonepedroaa theimpactofbalancedreciprocaltranslocation46xxt717p13q24probablyinvolvingthesox9geneintheinvitrofertilizationwithownoocytesevaluatedbypreimplantationgenetictestingordonatedoocytes
AT peregrinopedrofm impactofbalancedreciprocaltranslocation46xxt717p13q24probablyinvolvingthesox9geneintheinvitrofertilizationwithownoocytesevaluatedbypreimplantationgenetictestingordonatedoocytes
AT gomesalecsandra impactofbalancedreciprocaltranslocation46xxt717p13q24probablyinvolvingthesox9geneintheinvitrofertilizationwithownoocytesevaluatedbypreimplantationgenetictestingordonatedoocytes
AT fujiimariana impactofbalancedreciprocaltranslocation46xxt717p13q24probablyinvolvingthesox9geneintheinvitrofertilizationwithownoocytesevaluatedbypreimplantationgenetictestingordonatedoocytes
AT bonettitatianacs impactofbalancedreciprocaltranslocation46xxt717p13q24probablyinvolvingthesox9geneintheinvitrofertilizationwithownoocytesevaluatedbypreimplantationgenetictestingordonatedoocytes
AT riboldimarcia impactofbalancedreciprocaltranslocation46xxt717p13q24probablyinvolvingthesox9geneintheinvitrofertilizationwithownoocytesevaluatedbypreimplantationgenetictestingordonatedoocytes
AT monteleonepedroaa impactofbalancedreciprocaltranslocation46xxt717p13q24probablyinvolvingthesox9geneintheinvitrofertilizationwithownoocytesevaluatedbypreimplantationgenetictestingordonatedoocytes

Ejemplares similares