Cargando…
A comparative cross-sectional study of prevalence and intensity of soil-transmitted helminthic infection between healthy and severe acutely malnourished pre-school aged children in Kano, Northern Nigeria
BACKGROUND: Soil-transmitted helminthic (STH) infections are common in Sub-Saharan Africa. One method used for control of these helminths is mass anti-helminthic administration in populations at risk of STH infections. In this regard, empiric treatment of children with Severe Acute Malnutrition (SAM...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364394/ https://www.ncbi.nlm.nih.gov/pubmed/30727974 http://dx.doi.org/10.1186/s12879-019-3755-3 |
_version_ | 1783393261350551552 |
---|---|
author | Imam, Abdulazeez Farouk, Zubaida L. Hassan-Hanga, Fatimah Ihesiulor, Uchechukwu G. |
author_facet | Imam, Abdulazeez Farouk, Zubaida L. Hassan-Hanga, Fatimah Ihesiulor, Uchechukwu G. |
author_sort | Imam, Abdulazeez |
collection | PubMed |
description | BACKGROUND: Soil-transmitted helminthic (STH) infections are common in Sub-Saharan Africa. One method used for control of these helminths is mass anti-helminthic administration in populations at risk of STH infections. In this regard, empiric treatment of children with Severe Acute Malnutrition (SAM) for STH infection is practiced in this region. It is however unclear if children with SAM suffer more from STH infection than healthy children. The objective of this study was to compare prevalence and intensity of STH infection between pre-school aged children with SAM and healthy children. METHODS: We approached 1114 pre-school aged children attending care in two health facilities in Kano, Nigeria to partake in this study. Of this number, we recruited 620 (55.7%) children, comprising 310 well-nourished children from well-baby clinics and 310 children with SAM from Community Management for Acute Malnutrition (CMAM) centres in these facilities. We assessed their nutritional status using World Health Organisation (WHO) growth charts and collected stool samples which we analysed using Formal-Ether Concentration technique to identify STH infection and Stoll’s technique to assess intensities of STH infection. We fitted a logistic regression model to determine if there was any association between nutrition status and helminthic infection, adjusting for the confounding effects of socio-economic status and age. We compared intensity of STH infection (measured as eggs per gram of faeces) between both nutrition groups using the independent t-test. RESULTS: Overall STH prevalence in our population was low (2.7%) and we found no significant association between nutritional status and presence of STH infection (OR = 1.10, 95% CI 0.38 to 3.21). Majority of our study participants had either low or moderate (94.2%) and there was no statistically significant difference between intensity of STH infection (t value = − 1.52, P value = 0.13) in children with SAM and those who were well-nourished. CONCLUSIONS: The overall STH prevalence among pre-school children was low in Kano and we did not find prevalence and intensity of STH infection to differ significantly between preschool children with SAM and well-nourished children. Our findings confirm the WHO recommendation that at low levels of prevalence and intensity, interventions to control STH are unnecessary. |
format | Online Article Text |
id | pubmed-6364394 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-63643942019-02-15 A comparative cross-sectional study of prevalence and intensity of soil-transmitted helminthic infection between healthy and severe acutely malnourished pre-school aged children in Kano, Northern Nigeria Imam, Abdulazeez Farouk, Zubaida L. Hassan-Hanga, Fatimah Ihesiulor, Uchechukwu G. BMC Infect Dis Research Article BACKGROUND: Soil-transmitted helminthic (STH) infections are common in Sub-Saharan Africa. One method used for control of these helminths is mass anti-helminthic administration in populations at risk of STH infections. In this regard, empiric treatment of children with Severe Acute Malnutrition (SAM) for STH infection is practiced in this region. It is however unclear if children with SAM suffer more from STH infection than healthy children. The objective of this study was to compare prevalence and intensity of STH infection between pre-school aged children with SAM and healthy children. METHODS: We approached 1114 pre-school aged children attending care in two health facilities in Kano, Nigeria to partake in this study. Of this number, we recruited 620 (55.7%) children, comprising 310 well-nourished children from well-baby clinics and 310 children with SAM from Community Management for Acute Malnutrition (CMAM) centres in these facilities. We assessed their nutritional status using World Health Organisation (WHO) growth charts and collected stool samples which we analysed using Formal-Ether Concentration technique to identify STH infection and Stoll’s technique to assess intensities of STH infection. We fitted a logistic regression model to determine if there was any association between nutrition status and helminthic infection, adjusting for the confounding effects of socio-economic status and age. We compared intensity of STH infection (measured as eggs per gram of faeces) between both nutrition groups using the independent t-test. RESULTS: Overall STH prevalence in our population was low (2.7%) and we found no significant association between nutritional status and presence of STH infection (OR = 1.10, 95% CI 0.38 to 3.21). Majority of our study participants had either low or moderate (94.2%) and there was no statistically significant difference between intensity of STH infection (t value = − 1.52, P value = 0.13) in children with SAM and those who were well-nourished. CONCLUSIONS: The overall STH prevalence among pre-school children was low in Kano and we did not find prevalence and intensity of STH infection to differ significantly between preschool children with SAM and well-nourished children. Our findings confirm the WHO recommendation that at low levels of prevalence and intensity, interventions to control STH are unnecessary. BioMed Central 2019-02-06 /pmc/articles/PMC6364394/ /pubmed/30727974 http://dx.doi.org/10.1186/s12879-019-3755-3 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Imam, Abdulazeez Farouk, Zubaida L. Hassan-Hanga, Fatimah Ihesiulor, Uchechukwu G. A comparative cross-sectional study of prevalence and intensity of soil-transmitted helminthic infection between healthy and severe acutely malnourished pre-school aged children in Kano, Northern Nigeria |
title | A comparative cross-sectional study of prevalence and intensity of soil-transmitted helminthic infection between healthy and severe acutely malnourished pre-school aged children in Kano, Northern Nigeria |
title_full | A comparative cross-sectional study of prevalence and intensity of soil-transmitted helminthic infection between healthy and severe acutely malnourished pre-school aged children in Kano, Northern Nigeria |
title_fullStr | A comparative cross-sectional study of prevalence and intensity of soil-transmitted helminthic infection between healthy and severe acutely malnourished pre-school aged children in Kano, Northern Nigeria |
title_full_unstemmed | A comparative cross-sectional study of prevalence and intensity of soil-transmitted helminthic infection between healthy and severe acutely malnourished pre-school aged children in Kano, Northern Nigeria |
title_short | A comparative cross-sectional study of prevalence and intensity of soil-transmitted helminthic infection between healthy and severe acutely malnourished pre-school aged children in Kano, Northern Nigeria |
title_sort | comparative cross-sectional study of prevalence and intensity of soil-transmitted helminthic infection between healthy and severe acutely malnourished pre-school aged children in kano, northern nigeria |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364394/ https://www.ncbi.nlm.nih.gov/pubmed/30727974 http://dx.doi.org/10.1186/s12879-019-3755-3 |
work_keys_str_mv | AT imamabdulazeez acomparativecrosssectionalstudyofprevalenceandintensityofsoiltransmittedhelminthicinfectionbetweenhealthyandsevereacutelymalnourishedpreschoolagedchildreninkanonorthernnigeria AT faroukzubaidal acomparativecrosssectionalstudyofprevalenceandintensityofsoiltransmittedhelminthicinfectionbetweenhealthyandsevereacutelymalnourishedpreschoolagedchildreninkanonorthernnigeria AT hassanhangafatimah acomparativecrosssectionalstudyofprevalenceandintensityofsoiltransmittedhelminthicinfectionbetweenhealthyandsevereacutelymalnourishedpreschoolagedchildreninkanonorthernnigeria AT ihesiuloruchechukwug acomparativecrosssectionalstudyofprevalenceandintensityofsoiltransmittedhelminthicinfectionbetweenhealthyandsevereacutelymalnourishedpreschoolagedchildreninkanonorthernnigeria AT imamabdulazeez comparativecrosssectionalstudyofprevalenceandintensityofsoiltransmittedhelminthicinfectionbetweenhealthyandsevereacutelymalnourishedpreschoolagedchildreninkanonorthernnigeria AT faroukzubaidal comparativecrosssectionalstudyofprevalenceandintensityofsoiltransmittedhelminthicinfectionbetweenhealthyandsevereacutelymalnourishedpreschoolagedchildreninkanonorthernnigeria AT hassanhangafatimah comparativecrosssectionalstudyofprevalenceandintensityofsoiltransmittedhelminthicinfectionbetweenhealthyandsevereacutelymalnourishedpreschoolagedchildreninkanonorthernnigeria AT ihesiuloruchechukwug comparativecrosssectionalstudyofprevalenceandintensityofsoiltransmittedhelminthicinfectionbetweenhealthyandsevereacutelymalnourishedpreschoolagedchildreninkanonorthernnigeria |