Cargando…

Focal adhesion kinase (FAK) activation by estrogens involves GPER in triple-negative breast cancer cells

BACKGROUND: Focal adhesion kinase (FAK) is a cytoplasmatic protein tyrosine kinase that associates with both integrins and growth factor receptors toward the adhesion, migration and invasion of cancer cells. The G-protein coupled estrogen receptor (GPER) has been involved in the stimulatory action o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rigiracciolo, Damiano Cosimo, Santolla, Maria Francesca, Lappano, Rosamaria, Vivacqua, Adele, Cirillo, Francesca, Galli, Giulia Raffaella, Talia, Marianna, Muglia, Lucia, Pellegrino, Michele, Nohata, Nijiro, Di Martino, Maria Teresa, Maggiolini, Marcello
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364402/ https://www.ncbi.nlm.nih.gov/pubmed/30728047 http://dx.doi.org/10.1186/s13046-019-1056-8

Ejemplares similares

GPER Mediates a Feedforward FGF2/FGFR1 Paracrine Activation Coupling CAFs to Cancer Cells toward Breast Tumor Progression
por: Santolla, Maria Francesca, et al.
Publicado: (2019)

miR-338-3p Is Regulated by Estrogens through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts (CAFs)
por: Vivacqua, Adele, et al.
Publicado: (2018)

IGF-1/IGF-1R/FAK/YAP Transduction Signaling Prompts Growth Effects in Triple-Negative Breast Cancer (TNBC) Cells
por: Rigiracciolo, Damiano Cosimo, et al.
Publicado: (2020)

Correction: Rigiracciolo, D.C., et al., IGF-1/IGF-1R/FAK/YAP Transduction Signaling Prompts Growth Effects in Triple-Negative Breast Cancer (TNBC) Cells. Cells 2020, 9, 1010
por: Rigiracciolo, Damiano Cosimo, et al.
Publicado: (2020)

Focal Adhesion Kinase Fine Tunes Multifaced Signals toward Breast Cancer Progression
por: Rigiracciolo, Damiano Cosimo, et al.
Publicado: (2021)

Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC)
por: Rigiracciolo, Damiano Cosimo, et al.
Publicado: (2022)

Stimulatory actions of IGF-I are mediated by IGF-IR cross-talk with GPER and DDR1 in mesothelioma and lung cancer cells
por: Avino, Silvia, et al.
Publicado: (2016)

Copper activates HIF-1α/GPER/VEGF signalling in cancer cells
por: Rigiracciolo, Damiano Cosimo, et al.
Publicado: (2015)

GPER is involved in the regulation of the estrogen-metabolizing CYP1B1 enzyme in breast cancer
por: Cirillo, Francesca, et al.
Publicado: (2017)

GPER deletion triggers inhibitory effects in triple negative breast cancer (TNBC) cells through the JNK/c-Jun/p53/Noxa transduction pathway
por: Cirillo, Francesca, et al.
Publicado: (2023)

miR-221 stimulates breast cancer cells and cancer-associated fibroblasts (CAFs) through selective interference with the A20/c-Rel/CTGF signaling
por: Santolla, Maria Francesca, et al.
Publicado: (2018)

GPER is involved in the stimulatory effects of aldosterone in breast cancer cells and breast tumor-derived endothelial cells
por: Rigiracciolo, Damiano Cosimo, et al.
Publicado: (2015)

SIRT1 is involved in oncogenic signaling mediated by GPER in breast cancer
por: Santolla, M F, et al.
Publicado: (2015)

Estrogenic gper signaling regulates mir144 expression in cancer cells and cancer-associated fibroblasts (cafs)
por: Vivacqua, Adele, et al.
Publicado: (2015)

The G Protein-Coupled Estrogen Receptor (GPER) Expression Correlates with Pro-Metastatic Pathways in ER-Negative Breast Cancer: A Bioinformatics Analysis
por: Talia, Marianna, et al.
Publicado: (2020)

MIBE acts as antagonist ligand of both estrogen receptor α and GPER in breast cancer cells
por: Lappano, Rosamaria, et al.
Publicado: (2012)

HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs)
por: De Francesco, Ernestina Marianna, et al.
Publicado: (2013)

Metformin counteracts stimulatory effects induced by insulin in primary breast cancer cells
por: Scordamaglia, Domenica, et al.
Publicado: (2022)

Computational Approaches for the Discovery of GPER Targeting Compounds
por: Grande, Fedora, et al.
Publicado: (2020)

GPER Function in Breast Cancer: An Overview
por: Lappano, Rosamaria, et al.
Publicado: (2014)

GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response
por: De Marco, Paola, et al.
Publicado: (2016)

The lauric acid-activated signaling prompts apoptosis in cancer cells
por: Lappano, Rosamaria, et al.
Publicado: (2017)

Bisphenol A Induces Gene Expression Changes and Proliferative Effects through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts
por: Pupo, Marco, et al.
Publicado: (2012)

Estrogen receptor variant ERα46 and insulin receptor drive in primary breast cancer cells growth effects and interleukin 11 induction prompting the motility of cancer‐associated fibroblasts
por: Cirillo, Francesca, et al.
Publicado: (2021)

The IL1β-IL1R signaling is involved in the stimulatory effects triggered by hypoxia in breast cancer cells and cancer-associated fibroblasts (CAFs)
por: Lappano, Rosamaria, et al.
Publicado: (2020)

A calixpyrrole derivative acts as an antagonist to GPER, a G-protein coupled receptor: mechanisms and models
por: Lappano, Rosamaria, et al.
Publicado: (2015)

AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs)
por: Cirillo, Francesca, et al.
Publicado: (2019)

The Peptide ERα17p Is a GPER Inverse Agonist that Exerts Antiproliferative Effects in Breast Cancer Cells
por: Lappano, Rosamaria, et al.
Publicado: (2019)

Promising Perspectives of the Antiproliferative GPER Inverse Agonist ERα17p in Breast Cancer
por: Kampa, Marilena, et al.
Publicado: (2023)

S100A4 Is Involved in Stimulatory Effects Elicited by the FGF2/FGFR1 Signaling Pathway in Triple-Negative Breast Cancer (TNBC) Cells
por: Santolla, Maria Francesca, et al.
Publicado: (2021)

The AGEs/RAGE Transduction Signaling Prompts IL-8/CXCR1/2-Mediated Interaction between Cancer-Associated Fibroblasts (CAFs) and Breast Cancer Cells
por: Santolla, Maria Francesca, et al.
Publicado: (2022)

GPER1 and microRNA: Two Players in Breast Cancer Progression
por: Vivacqua, Adele
Publicado: (2020)

Notch1 Mediates Preconditioning Protection Induced by GPER in Normotensive and Hypertensive Female Rat Hearts
por: Rocca, Carmine, et al.
Publicado: (2018)

Pregnancy Augments G Protein Estrogen Receptor (GPER) Induced Vasodilation in Rat Uterine Arteries via the Nitric Oxide - cGMP Signaling Pathway
por: Tropea, Teresa, et al.
Publicado: (2015)

The Ephrin tyrosine kinase a3 (EphA3) is a novel mediator of RAGE-prompted motility of breast cancer cells
por: Talia, Marianna, et al.
Publicado: (2023)

The FGF/FGFR System in Breast Cancer: Oncogenic Features and Therapeutic Perspectives
por: Santolla, Maria Francesca, et al.
Publicado: (2020)

Novel Aspects Concerning the Functional Cross-Talk between the Insulin/IGF-I System and Estrogen Signaling in Cancer Cells
por: De Marco, Paola, et al.
Publicado: (2015)

Interaction of the Anti-Proliferative GPER Inverse Agonist ERα17p with the Breast Cancer Cell Plasma Membrane: From Biophysics to Biology
por: Trichet, Michaël, et al.
Publicado: (2020)

Identification of a human estrogen receptor α tetrapeptidic fragment with dual antiproliferative and anti-nociceptive action
por: Jouffre, Baptiste, et al.
Publicado: (2023)

Identification of the estrogen receptor GPER in neoplastic and non-neoplastic human testes
por: Rago, Vittoria, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_gfip1c771rf32db2m1e168iian