The Effectiveness of Oral Mini-Pulse Methylprednisolonein - the Treatment of Alopecia Areata in Vietnam

BACKGROUND: Systemic corticosteroid is used to treat alopecia areata, but it is associated with side effects. Mini-pulse therapy is thought to be effective but able to reduce side effects. AIM: The study aimed to evaluate the effectiveness of oral mini-pulse methylprednisolone in the treatment of al...

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Autores principales: Thi, Phuong Trinh, Lan, Anh Tran, Ha, Phuong Tran Thu, Van, Thuong Nguyen, Minh, Phuong Pham Thi, Trong, Hao Nguyen, Van, Tro Chau, Huu, Nghi Dinh, Cam, Van Tran, Huyen, My Le, Hau, Khang Tran, Gandolfi, Marco, Satolli, Francesca, Feliciani, Claudio, Tirant, Michael, Vojvodic, Aleksandra, Lotti, Torello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Republic of Macedonia 2019
Materias:
Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364712/
https://www.ncbi.nlm.nih.gov/pubmed/30745983
http://dx.doi.org/10.3889/oamjms.2019.097
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author Thi, Phuong Trinh
Lan, Anh Tran
Ha, Phuong Tran Thu
Van, Thuong Nguyen
Minh, Phuong Pham Thi
Trong, Hao Nguyen
Van, Tro Chau
Huu, Nghi Dinh
Cam, Van Tran
Huyen, My Le
Hau, Khang Tran
Gandolfi, Marco
Satolli, Francesca
Feliciani, Claudio
Tirant, Michael
Vojvodic, Aleksandra
Lotti, Torello
author_facet Thi, Phuong Trinh
Lan, Anh Tran
Ha, Phuong Tran Thu
Van, Thuong Nguyen
Minh, Phuong Pham Thi
Trong, Hao Nguyen
Van, Tro Chau
Huu, Nghi Dinh
Cam, Van Tran
Huyen, My Le
Hau, Khang Tran
Gandolfi, Marco
Satolli, Francesca
Feliciani, Claudio
Tirant, Michael
Vojvodic, Aleksandra
Lotti, Torello
author_sort Thi, Phuong Trinh
collection PubMed
description BACKGROUND: Systemic corticosteroid is used to treat alopecia areata, but it is associated with side effects. Mini-pulse therapy is thought to be effective but able to reduce side effects. AIM: The study aimed to evaluate the effectiveness of oral mini-pulse methylprednisolone in the treatment of alopecia areata. METHODS: Patients received methylprednisolone 16 mg orally for 2 consecutive days every week. RESULTS: After 3 months, among patients, 40% recovered well, and 55.6% recovered fairly. After 6 months, 82.2% recovered well, 17.8% recovered fairly. No adverse events were detected, and the recurrence rate was low (2.2%). CONCLUSION: Oral mini-pulse methylprednisolone therapy is an effective and safe therapeutic option for alopecia areata without side effects, and the time of the treatment is short.
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spelling pubmed-63647122019-02-11 The Effectiveness of Oral Mini-Pulse Methylprednisolonein - the Treatment of Alopecia Areata in Vietnam Thi, Phuong Trinh Lan, Anh Tran Ha, Phuong Tran Thu Van, Thuong Nguyen Minh, Phuong Pham Thi Trong, Hao Nguyen Van, Tro Chau Huu, Nghi Dinh Cam, Van Tran Huyen, My Le Hau, Khang Tran Gandolfi, Marco Satolli, Francesca Feliciani, Claudio Tirant, Michael Vojvodic, Aleksandra Lotti, Torello Open Access Maced J Med Sci Clinical Science BACKGROUND: Systemic corticosteroid is used to treat alopecia areata, but it is associated with side effects. Mini-pulse therapy is thought to be effective but able to reduce side effects. AIM: The study aimed to evaluate the effectiveness of oral mini-pulse methylprednisolone in the treatment of alopecia areata. METHODS: Patients received methylprednisolone 16 mg orally for 2 consecutive days every week. RESULTS: After 3 months, among patients, 40% recovered well, and 55.6% recovered fairly. After 6 months, 82.2% recovered well, 17.8% recovered fairly. No adverse events were detected, and the recurrence rate was low (2.2%). CONCLUSION: Oral mini-pulse methylprednisolone therapy is an effective and safe therapeutic option for alopecia areata without side effects, and the time of the treatment is short. Republic of Macedonia 2019-01-29 /pmc/articles/PMC6364712/ /pubmed/30745983 http://dx.doi.org/10.3889/oamjms.2019.097 Text en Copyright: © 2019 Phuong Trinh Thi, Anh Tran Lan, Phuong Tran Thu Ha, Thuong Nguyen Van, Phuong Pham Thi Minh, Hao Nguyen Trong, Tro Chau Van, Nghi Dinh Huu, Van Tran Cam, My Le Huyen, Khang Tran Hau, Marco Gandolfi, Francesca Satolli, Claudio Feliciani, Michael Tirant, Aleksandra Vojvodic, Torello Lotti. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).
spellingShingle Clinical Science
Thi, Phuong Trinh
Lan, Anh Tran
Ha, Phuong Tran Thu
Van, Thuong Nguyen
Minh, Phuong Pham Thi
Trong, Hao Nguyen
Van, Tro Chau
Huu, Nghi Dinh
Cam, Van Tran
Huyen, My Le
Hau, Khang Tran
Gandolfi, Marco
Satolli, Francesca
Feliciani, Claudio
Tirant, Michael
Vojvodic, Aleksandra
Lotti, Torello
The Effectiveness of Oral Mini-Pulse Methylprednisolonein - the Treatment of Alopecia Areata in Vietnam
title The Effectiveness of Oral Mini-Pulse Methylprednisolonein - the Treatment of Alopecia Areata in Vietnam
title_full The Effectiveness of Oral Mini-Pulse Methylprednisolonein - the Treatment of Alopecia Areata in Vietnam
title_fullStr The Effectiveness of Oral Mini-Pulse Methylprednisolonein - the Treatment of Alopecia Areata in Vietnam
title_full_unstemmed The Effectiveness of Oral Mini-Pulse Methylprednisolonein - the Treatment of Alopecia Areata in Vietnam
title_short The Effectiveness of Oral Mini-Pulse Methylprednisolonein - the Treatment of Alopecia Areata in Vietnam
title_sort effectiveness of oral mini-pulse methylprednisolonein - the treatment of alopecia areata in vietnam
topic Clinical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364712/
https://www.ncbi.nlm.nih.gov/pubmed/30745983
http://dx.doi.org/10.3889/oamjms.2019.097
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