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Efficacy of Surgical Excision for Nevus Sebaceous - Vietnamese Experience
BACKGROUND: Nevus Sebaceous (NS) is hamartoma predominantly composed of sebaceous glands and is classified as a type of epidermal nevus. In most case, clinical manifestation of NS is typical, so histopathology examination is important only in atypical lesions for its risk of malignancy. Clinical sym...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Republic of Macedonia
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364719/ https://www.ncbi.nlm.nih.gov/pubmed/30745961 http://dx.doi.org/10.3889/oamjms.2019.001 |
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author | Van, Thuong Nguyen Thanh, Hien Le Manh, Tan Nguyen Minh, Phuong Pham Thi Cao, Kiem Pham Hong, Sơn Nguyen Huu, Nghi Dinh Cam, Van Tran Huyen, My Le Hau, Khang Tran Gandolfi, Marco Satolli, Francesca Feliciani, Claudio Tirant, Michael Vojvodic, Aleksandra Lotti, Torello |
author_facet | Van, Thuong Nguyen Thanh, Hien Le Manh, Tan Nguyen Minh, Phuong Pham Thi Cao, Kiem Pham Hong, Sơn Nguyen Huu, Nghi Dinh Cam, Van Tran Huyen, My Le Hau, Khang Tran Gandolfi, Marco Satolli, Francesca Feliciani, Claudio Tirant, Michael Vojvodic, Aleksandra Lotti, Torello |
author_sort | Van, Thuong Nguyen |
collection | PubMed |
description | BACKGROUND: Nevus Sebaceous (NS) is hamartoma predominantly composed of sebaceous glands and is classified as a type of epidermal nevus. In most case, clinical manifestation of NS is typical, so histopathology examination is important only in atypical lesions for its risk of malignancy. Clinical symptoms are plaques or papules (100%), appearing in the head area (100%) with smooth surface (65.8%), usually with hair loss (60.7%). The histopathology is mostly characterized by the image of sebaceous gland hyperplasia (100%), no hair follicles (60.7%) or immature follicles (14.3%). AIM: The aim of our study is describing clinical and histopathological manifestation, make diagnosis and evaluate the best therapy. METHODS: Our study recruited 38 patients with NS, 3 patients (7.9%) with atypical aspects. All patients were treated by surgical excision. RESULTS: Complications as hair loss and infections were reported in 36.8% patients. No patients had recurrence after one year of treatment. CONCLUSION: Based upon our experience, surgery is cheap, simple, associated with high aesthetics effectiveness and low recurrence rate, proposing as the first choice for treatment of NS. |
format | Online Article Text |
id | pubmed-6364719 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Republic of Macedonia |
record_format | MEDLINE/PubMed |
spelling | pubmed-63647192019-02-11 Efficacy of Surgical Excision for Nevus Sebaceous - Vietnamese Experience Van, Thuong Nguyen Thanh, Hien Le Manh, Tan Nguyen Minh, Phuong Pham Thi Cao, Kiem Pham Hong, Sơn Nguyen Huu, Nghi Dinh Cam, Van Tran Huyen, My Le Hau, Khang Tran Gandolfi, Marco Satolli, Francesca Feliciani, Claudio Tirant, Michael Vojvodic, Aleksandra Lotti, Torello Open Access Maced J Med Sci Clinical Science BACKGROUND: Nevus Sebaceous (NS) is hamartoma predominantly composed of sebaceous glands and is classified as a type of epidermal nevus. In most case, clinical manifestation of NS is typical, so histopathology examination is important only in atypical lesions for its risk of malignancy. Clinical symptoms are plaques or papules (100%), appearing in the head area (100%) with smooth surface (65.8%), usually with hair loss (60.7%). The histopathology is mostly characterized by the image of sebaceous gland hyperplasia (100%), no hair follicles (60.7%) or immature follicles (14.3%). AIM: The aim of our study is describing clinical and histopathological manifestation, make diagnosis and evaluate the best therapy. METHODS: Our study recruited 38 patients with NS, 3 patients (7.9%) with atypical aspects. All patients were treated by surgical excision. RESULTS: Complications as hair loss and infections were reported in 36.8% patients. No patients had recurrence after one year of treatment. CONCLUSION: Based upon our experience, surgery is cheap, simple, associated with high aesthetics effectiveness and low recurrence rate, proposing as the first choice for treatment of NS. Republic of Macedonia 2019-01-24 /pmc/articles/PMC6364719/ /pubmed/30745961 http://dx.doi.org/10.3889/oamjms.2019.001 Text en Copyright: © 2019 Thuong Nguyen Van, Hien Le Thanh, Tan Nguyen Manh, Phuong Pham Thi Minh, Kiem Pham Cao, Sơn Nguyen Hong, Nghi Dinh Huu, Van Tran Cam, My Le Huyen, Khang Tran Hau, Marco Gandolfi, Francesca Satolli, Claudio Feliciani, Michael Tirant, Aleksandra Vojvodic, Torello Lotti. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0). |
spellingShingle | Clinical Science Van, Thuong Nguyen Thanh, Hien Le Manh, Tan Nguyen Minh, Phuong Pham Thi Cao, Kiem Pham Hong, Sơn Nguyen Huu, Nghi Dinh Cam, Van Tran Huyen, My Le Hau, Khang Tran Gandolfi, Marco Satolli, Francesca Feliciani, Claudio Tirant, Michael Vojvodic, Aleksandra Lotti, Torello Efficacy of Surgical Excision for Nevus Sebaceous - Vietnamese Experience |
title | Efficacy of Surgical Excision for Nevus Sebaceous - Vietnamese Experience |
title_full | Efficacy of Surgical Excision for Nevus Sebaceous - Vietnamese Experience |
title_fullStr | Efficacy of Surgical Excision for Nevus Sebaceous - Vietnamese Experience |
title_full_unstemmed | Efficacy of Surgical Excision for Nevus Sebaceous - Vietnamese Experience |
title_short | Efficacy of Surgical Excision for Nevus Sebaceous - Vietnamese Experience |
title_sort | efficacy of surgical excision for nevus sebaceous - vietnamese experience |
topic | Clinical Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364719/ https://www.ncbi.nlm.nih.gov/pubmed/30745961 http://dx.doi.org/10.3889/oamjms.2019.001 |
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