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Efficacy of Surgical Excision for Nevus Sebaceous - Vietnamese Experience

BACKGROUND: Nevus Sebaceous (NS) is hamartoma predominantly composed of sebaceous glands and is classified as a type of epidermal nevus. In most case, clinical manifestation of NS is typical, so histopathology examination is important only in atypical lesions for its risk of malignancy. Clinical sym...

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Autores principales: Van, Thuong Nguyen, Thanh, Hien Le, Manh, Tan Nguyen, Minh, Phuong Pham Thi, Cao, Kiem Pham, Hong, Sơn Nguyen, Huu, Nghi Dinh, Cam, Van Tran, Huyen, My Le, Hau, Khang Tran, Gandolfi, Marco, Satolli, Francesca, Feliciani, Claudio, Tirant, Michael, Vojvodic, Aleksandra, Lotti, Torello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Republic of Macedonia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364719/
https://www.ncbi.nlm.nih.gov/pubmed/30745961
http://dx.doi.org/10.3889/oamjms.2019.001
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author Van, Thuong Nguyen
Thanh, Hien Le
Manh, Tan Nguyen
Minh, Phuong Pham Thi
Cao, Kiem Pham
Hong, Sơn Nguyen
Huu, Nghi Dinh
Cam, Van Tran
Huyen, My Le
Hau, Khang Tran
Gandolfi, Marco
Satolli, Francesca
Feliciani, Claudio
Tirant, Michael
Vojvodic, Aleksandra
Lotti, Torello
author_facet Van, Thuong Nguyen
Thanh, Hien Le
Manh, Tan Nguyen
Minh, Phuong Pham Thi
Cao, Kiem Pham
Hong, Sơn Nguyen
Huu, Nghi Dinh
Cam, Van Tran
Huyen, My Le
Hau, Khang Tran
Gandolfi, Marco
Satolli, Francesca
Feliciani, Claudio
Tirant, Michael
Vojvodic, Aleksandra
Lotti, Torello
author_sort Van, Thuong Nguyen
collection PubMed
description BACKGROUND: Nevus Sebaceous (NS) is hamartoma predominantly composed of sebaceous glands and is classified as a type of epidermal nevus. In most case, clinical manifestation of NS is typical, so histopathology examination is important only in atypical lesions for its risk of malignancy. Clinical symptoms are plaques or papules (100%), appearing in the head area (100%) with smooth surface (65.8%), usually with hair loss (60.7%). The histopathology is mostly characterized by the image of sebaceous gland hyperplasia (100%), no hair follicles (60.7%) or immature follicles (14.3%). AIM: The aim of our study is describing clinical and histopathological manifestation, make diagnosis and evaluate the best therapy. METHODS: Our study recruited 38 patients with NS, 3 patients (7.9%) with atypical aspects. All patients were treated by surgical excision. RESULTS: Complications as hair loss and infections were reported in 36.8% patients. No patients had recurrence after one year of treatment. CONCLUSION: Based upon our experience, surgery is cheap, simple, associated with high aesthetics effectiveness and low recurrence rate, proposing as the first choice for treatment of NS.
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spelling pubmed-63647192019-02-11 Efficacy of Surgical Excision for Nevus Sebaceous - Vietnamese Experience Van, Thuong Nguyen Thanh, Hien Le Manh, Tan Nguyen Minh, Phuong Pham Thi Cao, Kiem Pham Hong, Sơn Nguyen Huu, Nghi Dinh Cam, Van Tran Huyen, My Le Hau, Khang Tran Gandolfi, Marco Satolli, Francesca Feliciani, Claudio Tirant, Michael Vojvodic, Aleksandra Lotti, Torello Open Access Maced J Med Sci Clinical Science BACKGROUND: Nevus Sebaceous (NS) is hamartoma predominantly composed of sebaceous glands and is classified as a type of epidermal nevus. In most case, clinical manifestation of NS is typical, so histopathology examination is important only in atypical lesions for its risk of malignancy. Clinical symptoms are plaques or papules (100%), appearing in the head area (100%) with smooth surface (65.8%), usually with hair loss (60.7%). The histopathology is mostly characterized by the image of sebaceous gland hyperplasia (100%), no hair follicles (60.7%) or immature follicles (14.3%). AIM: The aim of our study is describing clinical and histopathological manifestation, make diagnosis and evaluate the best therapy. METHODS: Our study recruited 38 patients with NS, 3 patients (7.9%) with atypical aspects. All patients were treated by surgical excision. RESULTS: Complications as hair loss and infections were reported in 36.8% patients. No patients had recurrence after one year of treatment. CONCLUSION: Based upon our experience, surgery is cheap, simple, associated with high aesthetics effectiveness and low recurrence rate, proposing as the first choice for treatment of NS. Republic of Macedonia 2019-01-24 /pmc/articles/PMC6364719/ /pubmed/30745961 http://dx.doi.org/10.3889/oamjms.2019.001 Text en Copyright: © 2019 Thuong Nguyen Van, Hien Le Thanh, Tan Nguyen Manh, Phuong Pham Thi Minh, Kiem Pham Cao, Sơn Nguyen Hong, Nghi Dinh Huu, Van Tran Cam, My Le Huyen, Khang Tran Hau, Marco Gandolfi, Francesca Satolli, Claudio Feliciani, Michael Tirant, Aleksandra Vojvodic, Torello Lotti. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).
spellingShingle Clinical Science
Van, Thuong Nguyen
Thanh, Hien Le
Manh, Tan Nguyen
Minh, Phuong Pham Thi
Cao, Kiem Pham
Hong, Sơn Nguyen
Huu, Nghi Dinh
Cam, Van Tran
Huyen, My Le
Hau, Khang Tran
Gandolfi, Marco
Satolli, Francesca
Feliciani, Claudio
Tirant, Michael
Vojvodic, Aleksandra
Lotti, Torello
Efficacy of Surgical Excision for Nevus Sebaceous - Vietnamese Experience
title Efficacy of Surgical Excision for Nevus Sebaceous - Vietnamese Experience
title_full Efficacy of Surgical Excision for Nevus Sebaceous - Vietnamese Experience
title_fullStr Efficacy of Surgical Excision for Nevus Sebaceous - Vietnamese Experience
title_full_unstemmed Efficacy of Surgical Excision for Nevus Sebaceous - Vietnamese Experience
title_short Efficacy of Surgical Excision for Nevus Sebaceous - Vietnamese Experience
title_sort efficacy of surgical excision for nevus sebaceous - vietnamese experience
topic Clinical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364719/
https://www.ncbi.nlm.nih.gov/pubmed/30745961
http://dx.doi.org/10.3889/oamjms.2019.001
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