Treatment of Multiple Myeloma in Elderly Patients: A Review of Literature and Practice Guidelines

Multiple myeloma (MM) is a clonal disorder of malignant plasma cells that comprises approximately 10% of hematologic malignancies. With median age of 66 at the time of presentation, multiple myeloma is predominantly a disease of the elderly. The availability of new combination regimens and the enhan...

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Detalles Bibliográficos
Autores principales: Manapuram, Suresh, Hashmi, Hamza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364954/
https://www.ncbi.nlm.nih.gov/pubmed/30761222
http://dx.doi.org/10.7759/cureus.3669
Descripción
Sumario:Multiple myeloma (MM) is a clonal disorder of malignant plasma cells that comprises approximately 10% of hematologic malignancies. With median age of 66 at the time of presentation, multiple myeloma is predominantly a disease of the elderly. The availability of new combination regimens and the enhanced safety of autologous hematopoietic stem cell transplant has increased the treatment options for elderly patients with multiple myeloma. We provide a summary of data supporting the current management of elderly patients with newly diagnosed multiple myeloma.

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