Treatment of Multiple Myeloma in Elderly Patients: A Review of Literature and Practice Guidelines

Multiple myeloma (MM) is a clonal disorder of malignant plasma cells that comprises approximately 10% of hematologic malignancies. With median age of 66 at the time of presentation, multiple myeloma is predominantly a disease of the elderly. The availability of new combination regimens and the enhan...

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Detalles Bibliográficos
Autores principales: Manapuram, Suresh, Hashmi, Hamza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364954/
https://www.ncbi.nlm.nih.gov/pubmed/30761222
http://dx.doi.org/10.7759/cureus.3669
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author Manapuram, Suresh
Hashmi, Hamza
author_facet Manapuram, Suresh
Hashmi, Hamza
author_sort Manapuram, Suresh
collection PubMed
description Multiple myeloma (MM) is a clonal disorder of malignant plasma cells that comprises approximately 10% of hematologic malignancies. With median age of 66 at the time of presentation, multiple myeloma is predominantly a disease of the elderly. The availability of new combination regimens and the enhanced safety of autologous hematopoietic stem cell transplant has increased the treatment options for elderly patients with multiple myeloma. We provide a summary of data supporting the current management of elderly patients with newly diagnosed multiple myeloma.
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spelling pubmed-63649542019-02-13 Treatment of Multiple Myeloma in Elderly Patients: A Review of Literature and Practice Guidelines Manapuram, Suresh Hashmi, Hamza Cureus Oncology Multiple myeloma (MM) is a clonal disorder of malignant plasma cells that comprises approximately 10% of hematologic malignancies. With median age of 66 at the time of presentation, multiple myeloma is predominantly a disease of the elderly. The availability of new combination regimens and the enhanced safety of autologous hematopoietic stem cell transplant has increased the treatment options for elderly patients with multiple myeloma. We provide a summary of data supporting the current management of elderly patients with newly diagnosed multiple myeloma. Cureus 2018-12-01 /pmc/articles/PMC6364954/ /pubmed/30761222 http://dx.doi.org/10.7759/cureus.3669 Text en Copyright © 2018, Manapuram et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Oncology
Manapuram, Suresh
Hashmi, Hamza
Treatment of Multiple Myeloma in Elderly Patients: A Review of Literature and Practice Guidelines
title Treatment of Multiple Myeloma in Elderly Patients: A Review of Literature and Practice Guidelines
title_full Treatment of Multiple Myeloma in Elderly Patients: A Review of Literature and Practice Guidelines
title_fullStr Treatment of Multiple Myeloma in Elderly Patients: A Review of Literature and Practice Guidelines
title_full_unstemmed Treatment of Multiple Myeloma in Elderly Patients: A Review of Literature and Practice Guidelines
title_short Treatment of Multiple Myeloma in Elderly Patients: A Review of Literature and Practice Guidelines
title_sort treatment of multiple myeloma in elderly patients: a review of literature and practice guidelines
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364954/
https://www.ncbi.nlm.nih.gov/pubmed/30761222
http://dx.doi.org/10.7759/cureus.3669
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