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A Case Series and Discussion on Surgical Treatment Strategy for Atypical Proximal Femoral Fractures Associated with Bisphosphonate Use

The aim of this study was to determine the incidence of atypical femoral fractures in our local population, study their current outcomes and present a novel surgical strategy based on these data. Patients who received surgical fixation of an atypical pattern proximal femoral fracture over a four-yea...

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Autores principales: Rocos, Brett, Fleming, Thomas, Harding, Karen, Acharya, Mehool, Riddick, Andrew, Kelly, Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364955/
https://www.ncbi.nlm.nih.gov/pubmed/30761223
http://dx.doi.org/10.7759/cureus.3670
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author Rocos, Brett
Fleming, Thomas
Harding, Karen
Acharya, Mehool
Riddick, Andrew
Kelly, Mike
author_facet Rocos, Brett
Fleming, Thomas
Harding, Karen
Acharya, Mehool
Riddick, Andrew
Kelly, Mike
author_sort Rocos, Brett
collection PubMed
description The aim of this study was to determine the incidence of atypical femoral fractures in our local population, study their current outcomes and present a novel surgical strategy based on these data. Patients who received surgical fixation of an atypical pattern proximal femoral fracture over a four-year period were identified and followed up in the clinic until union, revision surgery or death. The local incidence of atypical femoral fractures is 1.1 per 1000 per annum amongst patients receiving bisphosphonates. Twelve fixation procedures were carried out in 10 patients. Intra-operative reduction and nailing led to an average deformity of 8.5° varus and 13° apex anterior. Five cases required revision surgery. Fifty percent of primary procedures resulted in radiographic union within two years. We suggest that the lateral side of the fracture should be considered a primary nonunion. We advocate undertaking a wedge excision to correct the bone to a valgus morphology and stabilising with an intramedullary nail and a lateral tension plate. Multicentre studies are needed to demonstrate the efficacy of any particular approach.
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spelling pubmed-63649552019-02-13 A Case Series and Discussion on Surgical Treatment Strategy for Atypical Proximal Femoral Fractures Associated with Bisphosphonate Use Rocos, Brett Fleming, Thomas Harding, Karen Acharya, Mehool Riddick, Andrew Kelly, Mike Cureus Emergency Medicine The aim of this study was to determine the incidence of atypical femoral fractures in our local population, study their current outcomes and present a novel surgical strategy based on these data. Patients who received surgical fixation of an atypical pattern proximal femoral fracture over a four-year period were identified and followed up in the clinic until union, revision surgery or death. The local incidence of atypical femoral fractures is 1.1 per 1000 per annum amongst patients receiving bisphosphonates. Twelve fixation procedures were carried out in 10 patients. Intra-operative reduction and nailing led to an average deformity of 8.5° varus and 13° apex anterior. Five cases required revision surgery. Fifty percent of primary procedures resulted in radiographic union within two years. We suggest that the lateral side of the fracture should be considered a primary nonunion. We advocate undertaking a wedge excision to correct the bone to a valgus morphology and stabilising with an intramedullary nail and a lateral tension plate. Multicentre studies are needed to demonstrate the efficacy of any particular approach. Cureus 2018-12-02 /pmc/articles/PMC6364955/ /pubmed/30761223 http://dx.doi.org/10.7759/cureus.3670 Text en Copyright © 2018, Rocos et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Emergency Medicine
Rocos, Brett
Fleming, Thomas
Harding, Karen
Acharya, Mehool
Riddick, Andrew
Kelly, Mike
A Case Series and Discussion on Surgical Treatment Strategy for Atypical Proximal Femoral Fractures Associated with Bisphosphonate Use
title A Case Series and Discussion on Surgical Treatment Strategy for Atypical Proximal Femoral Fractures Associated with Bisphosphonate Use
title_full A Case Series and Discussion on Surgical Treatment Strategy for Atypical Proximal Femoral Fractures Associated with Bisphosphonate Use
title_fullStr A Case Series and Discussion on Surgical Treatment Strategy for Atypical Proximal Femoral Fractures Associated with Bisphosphonate Use
title_full_unstemmed A Case Series and Discussion on Surgical Treatment Strategy for Atypical Proximal Femoral Fractures Associated with Bisphosphonate Use
title_short A Case Series and Discussion on Surgical Treatment Strategy for Atypical Proximal Femoral Fractures Associated with Bisphosphonate Use
title_sort case series and discussion on surgical treatment strategy for atypical proximal femoral fractures associated with bisphosphonate use
topic Emergency Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364955/
https://www.ncbi.nlm.nih.gov/pubmed/30761223
http://dx.doi.org/10.7759/cureus.3670
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