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Predicting inadequate postoperative pain management in depressed patients: A machine learning approach

Widely-prescribed prodrug opioids (e.g., hydrocodone) require conversion by liver enzyme CYP-2D6 to exert their analgesic effects. The most commonly prescribed antidepressant, selective serotonin reuptake inhibitors (SSRIs), inhibits CYP-2D6 activity and therefore may reduce the effectiveness of pro...

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Detalles Bibliográficos
Autores principales:	Parthipan, Arjun, Banerjee, Imon, Humphreys, Keith, Asch, Steven M., Curtin, Catherine, Carroll, Ian, Hernandez-Boussard, Tina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364959/ https://www.ncbi.nlm.nih.gov/pubmed/30726237 http://dx.doi.org/10.1371/journal.pone.0210575

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