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Restriction of hepatitis B virus replication by c-Abl–induced proteasomal degradation of the viral polymerase
About 257 million people with chronic infection of hepatitis B virus (HBV) worldwide are at high risk of developing terminal liver diseases. Reactivation of virus replication has been frequently reported in those patient populations receiving imatinib (an Abl kinase inhibitor) or bortezomib (a prote...
Autores principales: | Hou, Lidan, Zhao, Jie, Gao, Shaobing, Ji, Tong, Song, Tianyu, Li, Yining, Wang, Jingjie, Geng, Chenlu, Long, Min, Chen, Jiang, Lin, Hui, Cai, Xiujun, Cang, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365112/ https://www.ncbi.nlm.nih.gov/pubmed/30775435 http://dx.doi.org/10.1126/sciadv.aau7130 |
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