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What concentration of tranexamic acid is needed to inhibit fibrinolysis? A systematic review of pharmacodynamics studies

Intravenous tranexamic acid (TXA) reduces death because of bleeding in patients with trauma and postpartum haemorrhage. However, in some settings intravenous injection is not feasible. To find different routes of administration, we first need to determine the minimal concentration of TXA in the bloo...

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Detalles Bibliográficos
Autores principales:	Picetti, Roberto, Shakur-Still, Haleema, Medcalf, Robert L., Standing, Joseph F., Roberts, Ian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams And Wilkins 2019
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365258/ https://www.ncbi.nlm.nih.gov/pubmed/30585835 http://dx.doi.org/10.1097/MBC.0000000000000789

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