Measles Virus-Based Treatments Trigger a Pro-inflammatory Cascade and a Distinctive Immunopeptidome in Glioblastoma

Glioblastoma is an aggressive primary brain tumor with bad prognosis. On the other hand, oncolytic measles virus (MeV) therapy is an experimental glioma treatment strategy with clinical safety and first evidence of anti-tumoral efficacy. Therefore, we investigated the combination of MeV with convent...

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Detalles Bibliográficos
Autores principales: Rajaraman, Srinath, Canjuga, Denis, Ghosh, Michael, Codrea, Marius Cosmin, Sieger, Raika, Wedekink, Florian, Tatagiba, Marcos, Koch, Marilin, Lauer, Ulrich M., Nahnsen, Sven, Rammensee, Hans-Georg, Mühlebach, Michael D., Stevanovic, Stefan, Tabatabai, Ghazaleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365369/
https://www.ncbi.nlm.nih.gov/pubmed/30775418
http://dx.doi.org/10.1016/j.omto.2018.12.010

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