TRIM44 promotes quiescent multiple myeloma cell occupancy and survival in the osteoblastic niche via HIF-1α stabilization

Despite progress in the treatment of MM, including the use of high-dose chemotherapy and autologous stem cell transplantation, a considerable proportion of patients are refractory to all therapies. This resistance is related to the molecular genetic heterogeneity in MM cells as well as to the contri...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Zheng, Lin, Tsung-Chin, Bi, Xiaohong, Lu, Guijin, Dawson, Brian C., Miranda, Roberto, Medeiros, L. Jeffrey, McNiece, Ian, McCarty, Nami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365383/
https://www.ncbi.nlm.nih.gov/pubmed/30089913
http://dx.doi.org/10.1038/s41375-018-0222-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365383/
https://www.ncbi.nlm.nih.gov/pubmed/30089913
http://dx.doi.org/10.1038/s41375-018-0222-x

Ejemplares similares