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Gene Expression Studies and Targeted Metabolomics Reveal Disturbed Serine, Methionine, and Tyrosine Metabolism in Early Hypertensive Nephrosclerosis

INTRODUCTION: Hypertensive nephrosclerosis is among the leading causes of end-stage renal disease, but its pathophysiology is poorly understood. We wanted to explore early metabolic changes using gene expression and targeted metabolomics analysis. METHODS: We analyzed gene expression in kidneys biop...

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Detalles Bibliográficos
Autores principales:	Øvrehus, Marius A., Bruheim, Per, Ju, Wenjun, Zelnick, Leila R., Langlo, Knut A., Sharma, Kumar, de Boer, Ian H., Hallan, Stein I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Translational Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365407/ https://www.ncbi.nlm.nih.gov/pubmed/30775629 http://dx.doi.org/10.1016/j.ekir.2018.10.007

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