Chaperone Mediated Autophagy in the Crosstalk of Neurodegenerative Diseases and Metabolic Disorders

Chaperone Mediated Autophagy (CMA) is a lysosomal-dependent protein degradation pathway. At least 30% of cytosolic proteins can be degraded by this process. The two major protein players of CMA are LAMP-2A and HSC70. While LAMP-2A works as a receptor for protein substrates at the lysosomal membrane,...

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Detalles Bibliográficos
Autores principales: Alfaro, Iván E., Albornoz, Amelina, Molina, Alfredo, Moreno, José, Cordero, Karina, Criollo, Alfredo, Budini, Mauricio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365421/
https://www.ncbi.nlm.nih.gov/pubmed/30766511
http://dx.doi.org/10.3389/fendo.2018.00778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365421/
https://www.ncbi.nlm.nih.gov/pubmed/30766511
http://dx.doi.org/10.3389/fendo.2018.00778

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