Cargando…

Chaperone Mediated Autophagy in the Crosstalk of Neurodegenerative Diseases and Metabolic Disorders

Chaperone Mediated Autophagy (CMA) is a lysosomal-dependent protein degradation pathway. At least 30% of cytosolic proteins can be degraded by this process. The two major protein players of CMA are LAMP-2A and HSC70. While LAMP-2A works as a receptor for protein substrates at the lysosomal membrane,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alfaro, Iván E., Albornoz, Amelina, Molina, Alfredo, Moreno, José, Cordero, Karina, Criollo, Alfredo, Budini, Mauricio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365421/ https://www.ncbi.nlm.nih.gov/pubmed/30766511 http://dx.doi.org/10.3389/fendo.2018.00778

Ejemplares similares

Chaperone Mediated Autophagy Degrades TDP-43 Protein and Is Affected by TDP-43 Aggregation
por: Ormeño, Fernando, et al.
Publicado: (2020)

Chaperone Mediated Autophagy Substrates and Components in Cancer
por: Rios, Javiera, et al.
Publicado: (2021)

Palmitic and Stearic Acids Inhibit Chaperone-Mediated Autophagy (CMA) in POMC-like Neurons In Vitro
por: Espinosa, Rodrigo, et al.
Publicado: (2022)

Autophagy and Its Impact on Neurodegenerative Diseases: New Roles for TDP-43 and C9orf72
por: Budini, Mauricio, et al.
Publicado: (2017)

Autophagy in aging-related oral diseases
por: Peña-Oyarzún, Daniel, et al.
Publicado: (2022)

New Roles of the Primary Cilium in Autophagy
por: Ávalos, Yenniffer, et al.
Publicado: (2017)

Polycystin-2 Is Required for Starvation- and Rapamycin-Induced Atrophy in Myotubes
por: Kretschmar, Catalina, et al.
Publicado: (2019)

Editorial: Selective and secretory autophagy pathways and molecules in the prevention and treatment of complex endocrine-metabolic diseases of aging
por: Vaccaro, Maria Ines, et al.
Publicado: (2023)

Hyperosmotic stress stimulates autophagy via polycystin-2
por: Peña-Oyarzun, Daniel, et al.
Publicado: (2017)

From Mouth to Brain: Neuroendocrine Markers Play as a Crosstalk Among Oral and Neurodegenerative Diseases
por: Tatullo, Marco, et al.
Publicado: (2019)

Crosstalk between MicroRNAs and Autophagy in Adult Neurogenesis: Implications for Neurodegenerative Disorders
por: Pircs, Karolina, et al.
Publicado: (2018)

Mitochondrial Chaperones in the Brain: Safeguarding Brain Health and Metabolism?
por: Castro, José Pedro, et al.
Publicado: (2018)

Chaperone-Mediated Autophagy Upregulation Rescues Megalin Expression and Localization in Cystinotic Proximal Tubule Cells
por: Zhang, Jinzhong, et al.
Publicado: (2019)

Impact of Chaperone-Mediated Autophagy in Brain Aging: Neurodegenerative Diseases and Glioblastoma
por: Auzmendi-Iriarte, Jaione, et al.
Publicado: (2021)

Chaperone-Mediated Autophagy in Neurodegenerative Diseases: Molecular Mechanisms and Pharmacological Opportunities
por: Wang, Yi-Ting, et al.
Publicado: (2022)

Autophagy and neurodegenerative disorders
por: Kesidou, Evangelia, et al.
Publicado: (2013)

Astrocyte-Neuron Metabolic Crosstalk in Neurodegeneration: A Mitochondrial Perspective
por: Mulica, Patrycja, et al.
Publicado: (2021)

Crosstalk Between Macroautophagy and Chaperone-Mediated Autophagy: Implications for the Treatment of Neurological Diseases
por: Wu, Haijian, et al.
Publicado: (2014)

PPARα: An emerging target of metabolic syndrome, neurodegenerative and cardiovascular diseases
por: Lin, Yijun, et al.
Publicado: (2022)

Mitochondrial Supercomplexes: Physiological Organization and Dysregulation in Age-Related Neurodegenerative Disorders
por: Novack, Gisela V., et al.
Publicado: (2020)

Origanum vulgare L. essential oil inhibits virulence patterns of Candida spp. and potentiates the effects of fluconazole and nystatin in vitro
por: Cid-Chevecich, Camila, et al.
Publicado: (2022)

Metabolic reprogramming and crosstalk of cancer-related fibroblasts and immune cells in the tumor microenvironment
por: Zhu, Yifei, et al.
Publicado: (2022)

Chaperone-Mediated Autophagy in Neurodegenerative Diseases and Acute Neurological Insults in the Central Nervous System
por: Kanno, Haruo, et al.
Publicado: (2022)

Targeting the non-classical estrogen pathway in neurodegenerative diseases and brain injury disorders
por: Koszegi, Zsombor, et al.
Publicado: (2022)

Interactions between β-arrestin proteins and the cytoskeletal system, and their relevance to neurodegenerative disorders
por: Szénási, Tibor, et al.
Publicado: (2023)

Mitoepigenetics and Neurodegenerative Diseases
por: Coppedè, Fabio, et al.
Publicado: (2019)

Editorial: The Unusual Presentation of Thyroid Disorders
por: Papi, Giampaolo, et al.
Publicado: (2019)

Profile of crosstalk between glucose and lipid metabolic disturbance and diabetic cardiomyopathy: Inflammation and oxidative stress
por: Chen, Meng-Yuan, et al.
Publicado: (2022)

Adipocyte-Endothelium Crosstalk in Obesity
por: Sabaratnam, Rugivan, et al.
Publicado: (2021)

Molecular Crosstalk Between Circadian Rhythmicity and the Development of Neurodegenerative Disorders
por: Sharma, Arastu, et al.
Publicado: (2020)

SIRT1 and Autophagy: Implications in Endocrine Disorders
por: Kim, Ji Yong, et al.
Publicado: (2022)

Editorial: Autophagy in Endocrine-Metabolic Diseases Associated With Aging
por: Vaccaro, Maria Ines, et al.
Publicado: (2020)

Secretory Autophagy and Its Relevance in Metabolic and Degenerative Disease
por: Gonzalez, Claudio Daniel, et al.
Publicado: (2020)

Contribution of Non-canonical Cortisol Actions in the Early Modulation of Glucose Metabolism of Gilthead Sea Bream (Sparus aurata)
por: Aedo, Jorge E., et al.
Publicado: (2019)

The Therapeutic Potential of Metformin in Neurodegenerative Diseases
por: Rotermund, Carola, et al.
Publicado: (2018)

The spectrum of neurodevelopmental, neuromuscular and neurodegenerative disorders due to defective autophagy
por: Deneubourg, Celine, et al.
Publicado: (2021)

Monitoring spatiotemporal changes in chaperone-mediated autophagy in vivo
por: Dong, S., et al.
Publicado: (2020)

Crosstalk between the Rho and Rab family of small GTPases in neurodegenerative disorders
por: Nik Akhtar, Shayan, et al.
Publicado: (2023)

Editorial: Metabolic Alterations in Neurodegenerative Disorders
por: Freude, Kristine K., et al.
Publicado: (2022)

Aging, Protein Aggregation, Chaperones, and Neurodegenerative Disorders: Mechanisms of Coupling and Therapeutic Opportunities
por: Cohen, Ehud
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_ip57bhvnm0h19o68irelaph5r4