Humanized Mouse Model Mimicking Pathology of Human Tuberculosis for in vivo Evaluation of Drug Regimens

Human immune system mice are highly valuable for in vivo dissection of human immune responses. Although they were employed for analyzing tuberculosis (TB) disease, there is little data on the spatial organization and cellular composition of human immune cells in TB granuloma pathology in this model....

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Detalles Bibliográficos
Autores principales: Arrey, Frida, Löwe, Delia, Kuhlmann, Stefanie, Kaiser, Peggy, Moura-Alves, Pedro, Krishnamoorthy, Gopinath, Lozza, Laura, Maertzdorf, Jeroen, Skrahina, Tatsiana, Skrahina, Alena, Gengenbacher, Martin, Nouailles, Geraldine, Kaufmann, Stefan H. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365439/
https://www.ncbi.nlm.nih.gov/pubmed/30766535
http://dx.doi.org/10.3389/fimmu.2019.00089

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