The affinity, intrinsic activity and selectivity of a structurally novel EP(2) receptor agonist at human prostanoid receptors

BACKGROUND AND PURPOSE: Prostanoid EP(2) receptor agonists exhibit several activities including ocular hypotension, tocolysis and anti‐inflammatory activity. This report describes the affinity and selectivity of a structurally novel, non‐prostanoid EP(2) receptor agonist, PGN‐9856, and its therapeut...

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Detalles Bibliográficos
Autores principales: Coleman, R A, Woodrooffe, A J, Clark, K L, Toris, C B, Fan, S, Wang, J W, Woodward, D F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365485/
https://www.ncbi.nlm.nih.gov/pubmed/30341781
http://dx.doi.org/10.1111/bph.14525

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