Recurrent activating STAT5B N642H mutation in myeloid neoplasms with eosinophilia

Determining the underlying cause of persistent eosinophilia is important for effective clinical management but remains a diagnostic challenge in many cases. We identified STAT5B N642H, an established oncogenic mutation, in 27/1715 (1.6%) cases referred for investigation of eosinophilia. Of the 27 mu...

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Detalles Bibliográficos
Autores principales: Cross, Nicholas C. P., Hoade, Yvette, Tapper, William J., Carreno-Tarragona, Gonzalo, Fanelli, Tiziana, Jawhar, Mohamad, Naumann, Nicole, Pieniak, Iwo, Lübke, Johannes, Ali, Sahra, Bhuller, Kaljit, Burgstaller, Sonja, Cargo, Catherine, Cavenagh, Jamie, Duncombe, Andrew S., Das-Gupta, Emma, Evans, Paul, Forsyth, Peter, George, Philip, Grimley, Charlotte, Jack, Fergus, Munro, Laura, Mehra, Varun, Patel, Kavita, Rismani, Ali, Sciuccati, Gabriela, Thomas-Dewing, Rowena, Thornton, Patrick, Virchis, Andres, Watt, Simon, Wallis, Louise, Whiteway, Alastair, Zegocki, Kris, Bain, Barbara J., Reiter, Andreas, Chase, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365490/
https://www.ncbi.nlm.nih.gov/pubmed/30573779
http://dx.doi.org/10.1038/s41375-018-0342-3

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