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Accelerating small-angle scattering experiments on anisotropic samples using kernel density estimation

We propose a method to accelerate small-angle scattering experiments by exploiting spatial correlation in two-dimensional data. We applied kernel density estimation to the average of a hundred short scans and evaluated noise reduction effects of kernel density estimation (smoothing). Although there...

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Autores principales: Saito, Kotaro, Yano, Masao, Hino, Hideitsu, Shoji, Tetsuya, Asahara, Akinori, Morita, Hidekazu, Mitsumata, Chiharu, Kohlbrecher, Joachim, Ono, Kanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365512/
https://www.ncbi.nlm.nih.gov/pubmed/30728390
http://dx.doi.org/10.1038/s41598-018-37345-5
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author Saito, Kotaro
Yano, Masao
Hino, Hideitsu
Shoji, Tetsuya
Asahara, Akinori
Morita, Hidekazu
Mitsumata, Chiharu
Kohlbrecher, Joachim
Ono, Kanta
author_facet Saito, Kotaro
Yano, Masao
Hino, Hideitsu
Shoji, Tetsuya
Asahara, Akinori
Morita, Hidekazu
Mitsumata, Chiharu
Kohlbrecher, Joachim
Ono, Kanta
author_sort Saito, Kotaro
collection PubMed
description We propose a method to accelerate small-angle scattering experiments by exploiting spatial correlation in two-dimensional data. We applied kernel density estimation to the average of a hundred short scans and evaluated noise reduction effects of kernel density estimation (smoothing). Although there is no advantage of using smoothing for isotropic data due to the powerful noise reduction effect of radial averaging, smoothing with a statistically and physically appropriate kernel can shorten measurement time by less than half to obtain sector averages with comparable statistical quality to that of sector averages without smoothing. This benefit will encourage researchers not to use full radial average on anisotropic data sacrificing anisotropy for statistical quality. We also confirmed that statistically reasonable estimation of measurement time is feasible on site by evaluating how intensity variances improve with accumulating counts. The noise reduction effect of smoothing will bring benefits to a wide range of applications from efficient use of beamtime at laboratories and large experimental facilities to stroboscopic measurements suffering low statistical quality.
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spelling pubmed-63655122019-02-08 Accelerating small-angle scattering experiments on anisotropic samples using kernel density estimation Saito, Kotaro Yano, Masao Hino, Hideitsu Shoji, Tetsuya Asahara, Akinori Morita, Hidekazu Mitsumata, Chiharu Kohlbrecher, Joachim Ono, Kanta Sci Rep Article We propose a method to accelerate small-angle scattering experiments by exploiting spatial correlation in two-dimensional data. We applied kernel density estimation to the average of a hundred short scans and evaluated noise reduction effects of kernel density estimation (smoothing). Although there is no advantage of using smoothing for isotropic data due to the powerful noise reduction effect of radial averaging, smoothing with a statistically and physically appropriate kernel can shorten measurement time by less than half to obtain sector averages with comparable statistical quality to that of sector averages without smoothing. This benefit will encourage researchers not to use full radial average on anisotropic data sacrificing anisotropy for statistical quality. We also confirmed that statistically reasonable estimation of measurement time is feasible on site by evaluating how intensity variances improve with accumulating counts. The noise reduction effect of smoothing will bring benefits to a wide range of applications from efficient use of beamtime at laboratories and large experimental facilities to stroboscopic measurements suffering low statistical quality. Nature Publishing Group UK 2019-02-06 /pmc/articles/PMC6365512/ /pubmed/30728390 http://dx.doi.org/10.1038/s41598-018-37345-5 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Saito, Kotaro
Yano, Masao
Hino, Hideitsu
Shoji, Tetsuya
Asahara, Akinori
Morita, Hidekazu
Mitsumata, Chiharu
Kohlbrecher, Joachim
Ono, Kanta
Accelerating small-angle scattering experiments on anisotropic samples using kernel density estimation
title Accelerating small-angle scattering experiments on anisotropic samples using kernel density estimation
title_full Accelerating small-angle scattering experiments on anisotropic samples using kernel density estimation
title_fullStr Accelerating small-angle scattering experiments on anisotropic samples using kernel density estimation
title_full_unstemmed Accelerating small-angle scattering experiments on anisotropic samples using kernel density estimation
title_short Accelerating small-angle scattering experiments on anisotropic samples using kernel density estimation
title_sort accelerating small-angle scattering experiments on anisotropic samples using kernel density estimation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365512/
https://www.ncbi.nlm.nih.gov/pubmed/30728390
http://dx.doi.org/10.1038/s41598-018-37345-5
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