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Accelerating small-angle scattering experiments on anisotropic samples using kernel density estimation
We propose a method to accelerate small-angle scattering experiments by exploiting spatial correlation in two-dimensional data. We applied kernel density estimation to the average of a hundred short scans and evaluated noise reduction effects of kernel density estimation (smoothing). Although there...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365512/ https://www.ncbi.nlm.nih.gov/pubmed/30728390 http://dx.doi.org/10.1038/s41598-018-37345-5 |
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author | Saito, Kotaro Yano, Masao Hino, Hideitsu Shoji, Tetsuya Asahara, Akinori Morita, Hidekazu Mitsumata, Chiharu Kohlbrecher, Joachim Ono, Kanta |
author_facet | Saito, Kotaro Yano, Masao Hino, Hideitsu Shoji, Tetsuya Asahara, Akinori Morita, Hidekazu Mitsumata, Chiharu Kohlbrecher, Joachim Ono, Kanta |
author_sort | Saito, Kotaro |
collection | PubMed |
description | We propose a method to accelerate small-angle scattering experiments by exploiting spatial correlation in two-dimensional data. We applied kernel density estimation to the average of a hundred short scans and evaluated noise reduction effects of kernel density estimation (smoothing). Although there is no advantage of using smoothing for isotropic data due to the powerful noise reduction effect of radial averaging, smoothing with a statistically and physically appropriate kernel can shorten measurement time by less than half to obtain sector averages with comparable statistical quality to that of sector averages without smoothing. This benefit will encourage researchers not to use full radial average on anisotropic data sacrificing anisotropy for statistical quality. We also confirmed that statistically reasonable estimation of measurement time is feasible on site by evaluating how intensity variances improve with accumulating counts. The noise reduction effect of smoothing will bring benefits to a wide range of applications from efficient use of beamtime at laboratories and large experimental facilities to stroboscopic measurements suffering low statistical quality. |
format | Online Article Text |
id | pubmed-6365512 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-63655122019-02-08 Accelerating small-angle scattering experiments on anisotropic samples using kernel density estimation Saito, Kotaro Yano, Masao Hino, Hideitsu Shoji, Tetsuya Asahara, Akinori Morita, Hidekazu Mitsumata, Chiharu Kohlbrecher, Joachim Ono, Kanta Sci Rep Article We propose a method to accelerate small-angle scattering experiments by exploiting spatial correlation in two-dimensional data. We applied kernel density estimation to the average of a hundred short scans and evaluated noise reduction effects of kernel density estimation (smoothing). Although there is no advantage of using smoothing for isotropic data due to the powerful noise reduction effect of radial averaging, smoothing with a statistically and physically appropriate kernel can shorten measurement time by less than half to obtain sector averages with comparable statistical quality to that of sector averages without smoothing. This benefit will encourage researchers not to use full radial average on anisotropic data sacrificing anisotropy for statistical quality. We also confirmed that statistically reasonable estimation of measurement time is feasible on site by evaluating how intensity variances improve with accumulating counts. The noise reduction effect of smoothing will bring benefits to a wide range of applications from efficient use of beamtime at laboratories and large experimental facilities to stroboscopic measurements suffering low statistical quality. Nature Publishing Group UK 2019-02-06 /pmc/articles/PMC6365512/ /pubmed/30728390 http://dx.doi.org/10.1038/s41598-018-37345-5 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Saito, Kotaro Yano, Masao Hino, Hideitsu Shoji, Tetsuya Asahara, Akinori Morita, Hidekazu Mitsumata, Chiharu Kohlbrecher, Joachim Ono, Kanta Accelerating small-angle scattering experiments on anisotropic samples using kernel density estimation |
title | Accelerating small-angle scattering experiments on anisotropic samples using kernel density estimation |
title_full | Accelerating small-angle scattering experiments on anisotropic samples using kernel density estimation |
title_fullStr | Accelerating small-angle scattering experiments on anisotropic samples using kernel density estimation |
title_full_unstemmed | Accelerating small-angle scattering experiments on anisotropic samples using kernel density estimation |
title_short | Accelerating small-angle scattering experiments on anisotropic samples using kernel density estimation |
title_sort | accelerating small-angle scattering experiments on anisotropic samples using kernel density estimation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365512/ https://www.ncbi.nlm.nih.gov/pubmed/30728390 http://dx.doi.org/10.1038/s41598-018-37345-5 |
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