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The Amazon rain forest plant Uncaria tomentosa (cat’s claw) and its specific proanthocyanidin constituents are potent inhibitors and reducers of both brain plaques and tangles

Brain aging and Alzheimer’s disease both demonstrate the accumulation of beta-amyloid protein containing “plaques” and tau protein containing “tangles” that contribute to accelerated memory loss and cognitive decline. In the present investigation we identified a specific plant extract and its consti...

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Detalles Bibliográficos
Autores principales: Snow, Alan D., Castillo, Gerardo M., Nguyen, Beth P., Choi, Paula Y., Cummings, Joel A., Cam, Judy, Hu, Qubai, Lake, Thomas, Pan, Weihong, Kastin, Abba J., Kirschner, Daniel A., Wood, Steven G., Rockenstein, Edward, Masliah, Eliezer, Lorimer, Stephen, Tanzi, Rudolph E., Larsen, Lesley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365538/
https://www.ncbi.nlm.nih.gov/pubmed/30728442
http://dx.doi.org/10.1038/s41598-019-38645-0