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The Amazon rain forest plant Uncaria tomentosa (cat’s claw) and its specific proanthocyanidin constituents are potent inhibitors and reducers of both brain plaques and tangles
Brain aging and Alzheimer’s disease both demonstrate the accumulation of beta-amyloid protein containing “plaques” and tau protein containing “tangles” that contribute to accelerated memory loss and cognitive decline. In the present investigation we identified a specific plant extract and its consti...
Autores principales: | Snow, Alan D., Castillo, Gerardo M., Nguyen, Beth P., Choi, Paula Y., Cummings, Joel A., Cam, Judy, Hu, Qubai, Lake, Thomas, Pan, Weihong, Kastin, Abba J., Kirschner, Daniel A., Wood, Steven G., Rockenstein, Edward, Masliah, Eliezer, Lorimer, Stephen, Tanzi, Rudolph E., Larsen, Lesley |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365538/ https://www.ncbi.nlm.nih.gov/pubmed/30728442 http://dx.doi.org/10.1038/s41598-019-38645-0 |
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