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Hematopoietic chimerism and donor-specific skin allograft tolerance after non-genotoxic CD117 antibody-drug-conjugate conditioning in MHC-mismatched allotransplantation

Hematopoietic chimerism after allogeneic bone marrow transplantation may establish a state of donor antigen-specific tolerance. However, current allotransplantation protocols involve genotoxic conditioning which has harmful side-effects and predisposes to infection and cancer. Here we describe a non...

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Detalles Bibliográficos
Autores principales: Li, Zhanzhuo, Czechowicz, Agnieszka, Scheck, Amelia, Rossi, Derrick J., Murphy, Philip M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365540/
https://www.ncbi.nlm.nih.gov/pubmed/30728353
http://dx.doi.org/10.1038/s41467-018-08202-w