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Effect of Chemical Permeation Enhancers on Skin Permeability: In silico screening using Molecular Dynamics simulations

Breaching of the skin barrier is essential for delivering active pharmaceutical ingredients (APIs) for pharmaceutical, dermatological and aesthetic applications. Chemical permeation enhancers (CPEs) are molecules that interact with the constituents of skin’s outermost and rate limiting layer stratum...

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Detalles Bibliográficos
Autores principales: Gupta, Rakesh, Dwadasi, Balarama Sridhar, Rai, Beena, Mitragotri, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365548/
https://www.ncbi.nlm.nih.gov/pubmed/30728438
http://dx.doi.org/10.1038/s41598-018-37900-0