Combined quantification of intracellular (phospho-)proteins and transcriptomics from fixed single cells

Environmental stimuli often lead to heterogeneous cellular responses and transcriptional output. We developed single-cell RNA and Immunodetection (RAID) to allow combined analysis of the transcriptome and intracellular (phospho-)proteins from fixed single cells. RAID successfully recapitulated diffe...

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Detalles Bibliográficos
Autores principales: Gerlach, Jan. P., van Buggenum, Jessie A. G., Tanis, Sabine E. J., Hogeweg, Mark, Heuts, Branco M. H., Muraro, Mauro J., Elze, Lisa, Rivello, Francesca, Rakszewska, Agata, van Oudenaarden, Alexander, Huck, Wilhelm T. S., Stunnenberg, Hendrik G., Mulder, Klaas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365588/
https://www.ncbi.nlm.nih.gov/pubmed/30728416
http://dx.doi.org/10.1038/s41598-018-37977-7

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