Targeted disruption of the Kcnj5 gene in the female mouse lowers aldosterone levels

Aldosterone is released from adrenal zona glomerulosa (ZG) cells and plays an important role in Na and K homoeostasis. Mutations in the human inwardly rectifying K channel CNJ type (KCNJ) 5 (KCNJ5) gene encoding the G-coupled inwardly rectifying K channel 4 (GIRK4) cause abnormal aldosterone secreti...

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Detalles Bibliográficos
Autores principales: Hardege, Iris, Long, Lu, Al Maskari, Raya, Figg, Nicola, O’Shaughnessy, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365593/
https://www.ncbi.nlm.nih.gov/pubmed/29222092
http://dx.doi.org/10.1042/CS20171285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365593/
https://www.ncbi.nlm.nih.gov/pubmed/29222092
http://dx.doi.org/10.1042/CS20171285

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