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The Glucoamylase Inhibitor Acarbose Has a Diet-Dependent and Reversible Effect on the Murine Gut Microbiome

Acarbose is a safe and effective medication for type 2 diabetes that inhibits host glucoamylases to prevent starch digestion in the small intestines and thus decrease postprandial blood glucose levels. This results in an increase in dietary starch in the distal intestine, where it becomes food for t...

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Detalles Bibliográficos
Autores principales: Baxter, Nielson T., Lesniak, Nicholas A., Sinani, Hamide, Schloss, Patrick D., Koropatkin, Nicole M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365613/
https://www.ncbi.nlm.nih.gov/pubmed/30728281
http://dx.doi.org/10.1128/mSphere.00528-18