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Robustness by intrinsically disordered C-termini and translational readthrough

During protein synthesis genetic instructions are passed from DNA via mRNA to the ribosome to assemble a protein chain. Occasionally, stop codons in the mRNA are bypassed and translation continues into the untranslated region (3′-UTR). This process, called translational readthrough (TR), yields a pr...

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Detalles Bibliográficos
Autores principales: Kleppe, April Snofrid, Bornberg-Bauer, Erich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365619/
https://www.ncbi.nlm.nih.gov/pubmed/30247639
http://dx.doi.org/10.1093/nar/gky778