Omalizumab and unmet needs in severe asthma and allergic comorbidities in Japanese children

Childhood asthma is one condition within a family of allergic diseases, which includes allergic rhinitis, atopic dermatitis, and food allergy, among others. Omalizumab is an anti-IgE antibody therapy that was approved in Japan for children with asthma and added to the Japanese pediatric asthma guide...

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Detalles Bibliográficos
Autores principales: Nishima, Sankei, Kozawa, Masanari, Milligan, Ki Lee, Papadopoulos, Nikolaos G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asia Pacific Association of Allergy, Asthma and Clinical Immunology 2019
Materias:
Educational & Teaching Material
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365659/
https://www.ncbi.nlm.nih.gov/pubmed/30740355
http://dx.doi.org/10.5415/apallergy.2019.9.e7
Descripción
Sumario:Childhood asthma is one condition within a family of allergic diseases, which includes allergic rhinitis, atopic dermatitis, and food allergy, among others. Omalizumab is an anti-IgE antibody therapy that was approved in Japan for children with asthma and added to the Japanese pediatric asthma guidelines in 2017. This review highlights the Japanese clinical perspectives in pediatric allergic asthma, and consideration for allergic comorbidities, and reflects on omalizumab clinical trials in progress to present comprehensive future opportunities.

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