Cargando…
Structural Analysis of Monoclonal Antibodies by Ultrahigh Resolution MALDI In-Source Decay FT-ICR Mass Spectrometry
[Image: see text] The emergence of complex protein therapeutics in general and monoclonal antibodies (mAbs) in particular have stimulated analytical chemists to develop new methods and strategies for their structural characterization. Mass spectrometry plays a key role in providing information on th...
Autores principales: | van der Burgt, Yuri E.M., Kilgour, David P. A., Tsybin, Yury O., Srzentić, Kristina, Fornelli, Luca, Beck, Alain, Wuhrer, Manfred, Nicolardi, Simone |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2018
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365908/ https://www.ncbi.nlm.nih.gov/pubmed/30571088 http://dx.doi.org/10.1021/acs.analchem.8b04515 |
Ejemplares similares
-
Monitoring glycation levels of a bispecific monoclonal antibody at subunit level by ultrahigh-resolution MALDI FT-ICR mass spectrometry
por: Gstöttner, Christoph, et al.
Publicado: (2019) -
Glycan and Protein Analysis of Glycoengineered Bacterial E. coli Vaccines by MALDI-in-Source Decay FT-ICR Mass Spectrometry
por: Nicolardi, Simone, et al.
Publicado: (2022) -
Improved N- and C-Terminal Sequencing of Proteins
by Combining Positive and Negative Ion MALDI In-Source Decay Mass
Spectrometry
por: Nicolardi, Simone, et al.
Publicado: (2020) -
Analysis of Synthetic Monodisperse Polysaccharides
by Wide Mass Range Ultrahigh-Resolution MALDI Mass Spectrometry
por: Nicolardi, Simone, et al.
Publicado: (2021) -
Evaluation of Sibling and Twin Fragment Ions Improves
the Structural Characterization of Proteins by Top-Down MALDI In-Source
Decay Mass Spectrometry
por: Nicolardi, Simone, et al.
Publicado: (2020)