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Romantic Surfaces: A Systematic Overview of Stable, Biospecific, and Antifouling Zwitterionic Surfaces
[Image: see text] This Feature Article focuses on recent advances in the bioconjugation of surface-bound zwitterionic polymers for biospecific antifouling surfaces. Various approaches for the functionalization of antifouling zwitterionic polymers are systematically investigated, such as chain-end an...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365910/ https://www.ncbi.nlm.nih.gov/pubmed/30620199 http://dx.doi.org/10.1021/acs.langmuir.8b03360 |
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author | Baggerman, Jacob Smulders, Maarten M. J. Zuilhof, Han |
author_facet | Baggerman, Jacob Smulders, Maarten M. J. Zuilhof, Han |
author_sort | Baggerman, Jacob |
collection | PubMed |
description | [Image: see text] This Feature Article focuses on recent advances in the bioconjugation of surface-bound zwitterionic polymers for biospecific antifouling surfaces. Various approaches for the functionalization of antifouling zwitterionic polymers are systematically investigated, such as chain-end and side-chain functionalization. Side-chain functionalization methods can be further classified as those that are achieved through homopolymerization of custom-synthesized zwitterionic monomers equipped with reactive groups, or those that are achieved via synthesis of random or block copolymers combining different monomers with antifouling functionality and others with reactive groups. Several of the pros and cons of these approaches are outlined and discussed. Finally, some perspective and future directions of research are presented toward long-term stable, generically repelling surfaces that strongly and specifically adhere to a single component in a complex mixture. |
format | Online Article Text |
id | pubmed-6365910 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | American
Chemical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-63659102019-02-08 Romantic Surfaces: A Systematic Overview of Stable, Biospecific, and Antifouling Zwitterionic Surfaces Baggerman, Jacob Smulders, Maarten M. J. Zuilhof, Han Langmuir [Image: see text] This Feature Article focuses on recent advances in the bioconjugation of surface-bound zwitterionic polymers for biospecific antifouling surfaces. Various approaches for the functionalization of antifouling zwitterionic polymers are systematically investigated, such as chain-end and side-chain functionalization. Side-chain functionalization methods can be further classified as those that are achieved through homopolymerization of custom-synthesized zwitterionic monomers equipped with reactive groups, or those that are achieved via synthesis of random or block copolymers combining different monomers with antifouling functionality and others with reactive groups. Several of the pros and cons of these approaches are outlined and discussed. Finally, some perspective and future directions of research are presented toward long-term stable, generically repelling surfaces that strongly and specifically adhere to a single component in a complex mixture. American Chemical Society 2019-01-08 2019-02-05 /pmc/articles/PMC6365910/ /pubmed/30620199 http://dx.doi.org/10.1021/acs.langmuir.8b03360 Text en Copyright © 2019 American Chemical Society This is an open access article published under a Creative Commons Non-Commercial No Derivative Works (CC-BY-NC-ND) Attribution License (http://pubs.acs.org/page/policy/authorchoice_ccbyncnd_termsofuse.html) , which permits copying and redistribution of the article, and creation of adaptations, all for non-commercial purposes. |
spellingShingle | Baggerman, Jacob Smulders, Maarten M. J. Zuilhof, Han Romantic Surfaces: A Systematic Overview of Stable, Biospecific, and Antifouling Zwitterionic Surfaces |
title | Romantic Surfaces: A Systematic Overview of Stable,
Biospecific, and Antifouling Zwitterionic Surfaces |
title_full | Romantic Surfaces: A Systematic Overview of Stable,
Biospecific, and Antifouling Zwitterionic Surfaces |
title_fullStr | Romantic Surfaces: A Systematic Overview of Stable,
Biospecific, and Antifouling Zwitterionic Surfaces |
title_full_unstemmed | Romantic Surfaces: A Systematic Overview of Stable,
Biospecific, and Antifouling Zwitterionic Surfaces |
title_short | Romantic Surfaces: A Systematic Overview of Stable,
Biospecific, and Antifouling Zwitterionic Surfaces |
title_sort | romantic surfaces: a systematic overview of stable,
biospecific, and antifouling zwitterionic surfaces |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365910/ https://www.ncbi.nlm.nih.gov/pubmed/30620199 http://dx.doi.org/10.1021/acs.langmuir.8b03360 |
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