Cargando…

Romantic Surfaces: A Systematic Overview of Stable, Biospecific, and Antifouling Zwitterionic Surfaces

[Image: see text] This Feature Article focuses on recent advances in the bioconjugation of surface-bound zwitterionic polymers for biospecific antifouling surfaces. Various approaches for the functionalization of antifouling zwitterionic polymers are systematically investigated, such as chain-end an...

Descripción completa

Detalles Bibliográficos
Autores principales: Baggerman, Jacob, Smulders, Maarten M. J., Zuilhof, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365910/
https://www.ncbi.nlm.nih.gov/pubmed/30620199
http://dx.doi.org/10.1021/acs.langmuir.8b03360
_version_ 1783393503115476992
author Baggerman, Jacob
Smulders, Maarten M. J.
Zuilhof, Han
author_facet Baggerman, Jacob
Smulders, Maarten M. J.
Zuilhof, Han
author_sort Baggerman, Jacob
collection PubMed
description [Image: see text] This Feature Article focuses on recent advances in the bioconjugation of surface-bound zwitterionic polymers for biospecific antifouling surfaces. Various approaches for the functionalization of antifouling zwitterionic polymers are systematically investigated, such as chain-end and side-chain functionalization. Side-chain functionalization methods can be further classified as those that are achieved through homopolymerization of custom-synthesized zwitterionic monomers equipped with reactive groups, or those that are achieved via synthesis of random or block copolymers combining different monomers with antifouling functionality and others with reactive groups. Several of the pros and cons of these approaches are outlined and discussed. Finally, some perspective and future directions of research are presented toward long-term stable, generically repelling surfaces that strongly and specifically adhere to a single component in a complex mixture.
format Online
Article
Text
id pubmed-6365910
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher American Chemical Society
record_format MEDLINE/PubMed
spelling pubmed-63659102019-02-08 Romantic Surfaces: A Systematic Overview of Stable, Biospecific, and Antifouling Zwitterionic Surfaces Baggerman, Jacob Smulders, Maarten M. J. Zuilhof, Han Langmuir [Image: see text] This Feature Article focuses on recent advances in the bioconjugation of surface-bound zwitterionic polymers for biospecific antifouling surfaces. Various approaches for the functionalization of antifouling zwitterionic polymers are systematically investigated, such as chain-end and side-chain functionalization. Side-chain functionalization methods can be further classified as those that are achieved through homopolymerization of custom-synthesized zwitterionic monomers equipped with reactive groups, or those that are achieved via synthesis of random or block copolymers combining different monomers with antifouling functionality and others with reactive groups. Several of the pros and cons of these approaches are outlined and discussed. Finally, some perspective and future directions of research are presented toward long-term stable, generically repelling surfaces that strongly and specifically adhere to a single component in a complex mixture. American Chemical Society 2019-01-08 2019-02-05 /pmc/articles/PMC6365910/ /pubmed/30620199 http://dx.doi.org/10.1021/acs.langmuir.8b03360 Text en Copyright © 2019 American Chemical Society This is an open access article published under a Creative Commons Non-Commercial No Derivative Works (CC-BY-NC-ND) Attribution License (http://pubs.acs.org/page/policy/authorchoice_ccbyncnd_termsofuse.html) , which permits copying and redistribution of the article, and creation of adaptations, all for non-commercial purposes.
spellingShingle Baggerman, Jacob
Smulders, Maarten M. J.
Zuilhof, Han
Romantic Surfaces: A Systematic Overview of Stable, Biospecific, and Antifouling Zwitterionic Surfaces
title Romantic Surfaces: A Systematic Overview of Stable, Biospecific, and Antifouling Zwitterionic Surfaces
title_full Romantic Surfaces: A Systematic Overview of Stable, Biospecific, and Antifouling Zwitterionic Surfaces
title_fullStr Romantic Surfaces: A Systematic Overview of Stable, Biospecific, and Antifouling Zwitterionic Surfaces
title_full_unstemmed Romantic Surfaces: A Systematic Overview of Stable, Biospecific, and Antifouling Zwitterionic Surfaces
title_short Romantic Surfaces: A Systematic Overview of Stable, Biospecific, and Antifouling Zwitterionic Surfaces
title_sort romantic surfaces: a systematic overview of stable, biospecific, and antifouling zwitterionic surfaces
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365910/
https://www.ncbi.nlm.nih.gov/pubmed/30620199
http://dx.doi.org/10.1021/acs.langmuir.8b03360
work_keys_str_mv AT baggermanjacob romanticsurfacesasystematicoverviewofstablebiospecificandantifoulingzwitterionicsurfaces
AT smuldersmaartenmj romanticsurfacesasystematicoverviewofstablebiospecificandantifoulingzwitterionicsurfaces
AT zuilhofhan romanticsurfacesasystematicoverviewofstablebiospecificandantifoulingzwitterionicsurfaces