Romidepsin suppresses monosodium urate crystal-induced cytokine production through upregulation of suppressor of cytokine signaling 1 expression

BACKGROUND: Acute gouty arthritis currently is the most common form of inflammatory arthritis in developed countries. Treatment is still suboptimal. Dosage of urate-lowering therapy is often too low to reach target urate levels, and adherence to therapy is poor. In this study, we therefore explore a...

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Detalles Bibliográficos
Autores principales: Cleophas, M. C. P., Crişan, T. O., Klück, V., Hoogerbrugge, N., Netea-Maier, R. T., Dinarello, C. A., Netea, M. G., Joosten, L. A. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366029/
https://www.ncbi.nlm.nih.gov/pubmed/30728075
http://dx.doi.org/10.1186/s13075-019-1834-x

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