Co-inhibition of PGF and VEGF blocks their expression in mononuclear phagocytes and limits neovascularization and leakage in the murine retina

BACKGROUND: Age-related macular degeneration (AMD) is a leading cause of visual impairment in the elderly. The neovascular (wet) form of AMD can be treated with intravitreal injections of different anti-vascular endothelial growth factor (VEGF) agents. Placental growth factor (PGF) is another member...

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Detalles Bibliográficos
Autores principales: Balser, Carsten, Wolf, Anne, Herb, Marc, Langmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366121/
https://www.ncbi.nlm.nih.gov/pubmed/30732627
http://dx.doi.org/10.1186/s12974-019-1419-2

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