Kratom (Mitragynine) Ingestion Requiring Naloxone Reversal

Kratom (mitragynine) is a naturally occurring opioid agonist whose use has been escalating. Its suppliers advertise it as a safe alternative for opioids and a safe treatment for opioid-withdrawal symptoms. There has been controversy in the past two years regarding the legal status and lack of regula...

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Detalles Bibliográficos
Autores principales: Overbeek, Daniel L., Abraham, Jonathan, Munzer, Brendan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: University of California Irvine, Department of Emergency Medicine publishing Western Journal of Emergency Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366391/
https://www.ncbi.nlm.nih.gov/pubmed/30775658
http://dx.doi.org/10.5811/cpcem.2018.11.40588
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author Overbeek, Daniel L.
Abraham, Jonathan
Munzer, Brendan W.
author_facet Overbeek, Daniel L.
Abraham, Jonathan
Munzer, Brendan W.
author_sort Overbeek, Daniel L.
collection PubMed
description Kratom (mitragynine) is a naturally occurring opioid agonist whose use has been escalating. Its suppliers advertise it as a safe alternative for opioids and a safe treatment for opioid-withdrawal symptoms. There has been controversy in the past two years regarding the legal status and lack of regulation surrounding kratom. Currently, kratom is legal and unregulated, leaving users at risk from unpredictable potencies and effects. We present the first case of successful naloxone reversal of opioid toxidrome from recreationally used kratom. We advocate further research and regulation to ensure standardized dosing to protect patients.
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spelling pubmed-63663912019-02-15 Kratom (Mitragynine) Ingestion Requiring Naloxone Reversal Overbeek, Daniel L. Abraham, Jonathan Munzer, Brendan W. Clin Pract Cases Emerg Med Case Report Kratom (mitragynine) is a naturally occurring opioid agonist whose use has been escalating. Its suppliers advertise it as a safe alternative for opioids and a safe treatment for opioid-withdrawal symptoms. There has been controversy in the past two years regarding the legal status and lack of regulation surrounding kratom. Currently, kratom is legal and unregulated, leaving users at risk from unpredictable potencies and effects. We present the first case of successful naloxone reversal of opioid toxidrome from recreationally used kratom. We advocate further research and regulation to ensure standardized dosing to protect patients. University of California Irvine, Department of Emergency Medicine publishing Western Journal of Emergency Medicine 2019-01-04 /pmc/articles/PMC6366391/ /pubmed/30775658 http://dx.doi.org/10.5811/cpcem.2018.11.40588 Text en Copyright: © 2019 Overbeek et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) License. See: http://creativecommons.org/licenses/by/4.0/
spellingShingle Case Report
Overbeek, Daniel L.
Abraham, Jonathan
Munzer, Brendan W.
Kratom (Mitragynine) Ingestion Requiring Naloxone Reversal
title Kratom (Mitragynine) Ingestion Requiring Naloxone Reversal
title_full Kratom (Mitragynine) Ingestion Requiring Naloxone Reversal
title_fullStr Kratom (Mitragynine) Ingestion Requiring Naloxone Reversal
title_full_unstemmed Kratom (Mitragynine) Ingestion Requiring Naloxone Reversal
title_short Kratom (Mitragynine) Ingestion Requiring Naloxone Reversal
title_sort kratom (mitragynine) ingestion requiring naloxone reversal
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366391/
https://www.ncbi.nlm.nih.gov/pubmed/30775658
http://dx.doi.org/10.5811/cpcem.2018.11.40588
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